School of Food Science and Technology, Faculty of Science and Technology, Thammasat University, 99 Mhu 18, Pahonyothin Road, Khong Luang, Pathum Thani 12120, Thailand; International Joint Research Center on Food Security, 113 Thailand Science Park, Phahonyothin Road, Khong Luang, Pathum Thani 12120, Thailand.
International Joint Research Center on Food Security, 113 Thailand Science Park, Phahonyothin Road, Khong Luang, Pathum Thani 12120, Thailand; Institute for Global Food Security, Queen's University, Belfast, Biological Sciences Building, 19 Chlorine Gardens, Belfast BT9 5DL, United Kingdom.
J Hazard Mater. 2022 Jun 15;432:128706. doi: 10.1016/j.jhazmat.2022.128706. Epub 2022 Mar 16.
Mycotoxins present serious threats not only for public health, but also for the economy and environment. The problems become more complex and serious due to co-contamination of multiple hazardous mycotoxins in commodities and environment. To mitigate against this issue, accurate, affordable, and rapid multiplex detection methods are required. This review presents an overview of emerging rapid immuno-based multiplex methods capable of detecting mycotoxins present in agricultural products and feed ingredients published within the past five years. The scientific principles, advantages, disadvantages, and assay performance of these rapid multiplex immunoassays, including lateral flow, fluorescence polarization, chemiluminescence, surface plasmon resonance, surface enhanced Raman scattering, electrochemical sensor, and nanoarray are discussed. From the recent literature landscape, it is predicted that the future trend of the detection methods for multiple mycotoxins will rely on the advance of various sensor technologies, a variety of enhancing and reporting signals based on nanomaterials, rapid and effective sample preparation, and capacity for quantitative analysis.
真菌毒素不仅对公共健康构成严重威胁，而且对经济和环境也构成严重威胁。由于商品和环境中多种有害真菌毒素的共同污染，问题变得更加复杂和严重。为了解决这个问题，需要准确、经济实惠且快速的多重检测方法。本综述介绍了过去五年内发表的用于检测农产品和饲料成分中存在的真菌毒素的新兴快速基于免疫的多重检测方法。讨论了这些快速多重免疫分析的科学原理、优点、缺点和分析性能，包括侧向流动、荧光偏振、化学发光、表面等离子体共振、表面增强拉曼散射、电化学传感器和纳米阵列。从最近的文献情况来看，可以预测，用于多种真菌毒素检测的方法的未来趋势将依赖于各种传感器技术的进步、基于纳米材料的各种增强和报告信号、快速有效的样品制备以及定量分析能力。
