Service de Réanimation médicale Pôle 2, Hôpital Louis Pasteur, Hôpitaux Civils de Colmar, Colmar, Grand-Est, France.
Service de Neurologie, Hôpital Louis Pasteur, Hôpitaux Civils de Colmar, Colmar, Grand-Est, France.
J Neuroimmunol. 2022 May 15;366:577842. doi: 10.1016/j.jneuroim.2022.577842. Epub 2022 Mar 5.
Various neurological complications have been described in COVID-19 patients, especially Guillain-Barre syndrome (GBS). The underlying mechanisms on the association between SARS-CoV-2 infection and GBS remain unclear, but several hypotheses have been proposed. It seems that post-SARS-CoV-2 GBS shares many characteristics with classic post-infectious GBS; however, it may occur in sedated and intubated patients hospitalized in the intensive care unit for SARS-CoV-2 acute respiratory distress syndrome, which presents challenges in the diagnosis and treatment of GBS. In this study, we describe three cases of post-SARS-CoV-2 GBS that were hospitalized in the intensive care unit.
在 COVID-19 患者中已经描述了各种神经并发症,尤其是吉兰-巴雷综合征(GBS)。SARS-CoV-2 感染与 GBS 之间的关联的潜在机制尚不清楚,但已经提出了几种假设。似乎 COVID-19 后 GBS 与经典感染后 GBS 有许多共同特征;然而,它可能发生在因 SARS-CoV-2 急性呼吸窘迫综合征而住院的 ICU 中接受镇静和插管的患者中,这给 GBS 的诊断和治疗带来了挑战。在本研究中,我们描述了 3 例住院于 ICU 的 COVID-19 后 GBS 病例。