Derar Derar, Ali Ahmed, Almundarij Tariq, Abd-Elmoniem Essam, Alhassun Tamim, Zeitoun Moustafa
Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Qassim University, Buraydah, Saudi Arabia.
Department of Theriogenology, Faculty of Veterinary Medicine, Assiut University, Assiut-71526, Egypt.
Vet Med Int. 2022 Mar 16;2022:8525089. doi: 10.1155/2022/8525089. eCollection 2022.
This study aimed to investigate the association of different reproductive disorders with the status of serum trace elements and steroid hormones in ewes and goats. This study included 131 barren and 11 fertile (control) ewes and 94 barren and 9 fertile (control) goats. Animals were examined gynecologically for reproductive soundness. The animals were bled, and their serum was harvested and assayed for manganese (Mn), selenium (Se), iron (Fe), zinc (Zn), estrogen (E2), and progesterone (P4) levels. The results showed that genital affections were associated with significant changes in serum Se (=0.001), Fe (=0.008), and Zn (=0.01) levels in ewes, as well as Mn (=0.01) levels in goats. Ewes and goats with cystic ovaries had higher serum Se, Fe, and Zn levels (=0.0001) than ewes with uterine affections, ovarian inactivity, and controls. Ovarian inactivity was linked to low Se levels in ewes and low Se and Zn levels in goats (=0.05). Ewes and goats with estrogen-dominant reproductive disorders had higher Se (=0.01), Fe (=0.03), and Zn (=0.01) compared with the control group. Se (=0.02) and Zn (=0.05) were lower in ewes and goats affected with P4-dominant genital disorders compared with the control group. It can be concluded that the reproductive disorders are associated with changes in the level of trace elements in blood of ewes and goats. There is a reciprocal relationship between the levels of estrogen and progesterone with those of the trace elements in serum of ewes and goats.
本研究旨在调查母羊和山羊不同生殖障碍与血清微量元素及类固醇激素水平之间的关联。本研究纳入了131只不孕母羊和11只可育（对照）母羊，以及94只不孕山羊和9只可育（对照）山羊。对动物进行妇科检查以评估生殖健康状况。采集动物血液，收获血清并检测其中锰（Mn）、硒（Se）、铁（Fe）、锌（Zn）、雌激素（E2）和孕酮（P4）的水平。结果显示，母羊的生殖器官病变与血清硒（=0.001）、铁（=0.008）和锌（=0.01）水平的显著变化相关，山羊则与锰（=0.01）水平变化相关。患有卵巢囊肿的母羊和山羊血清硒、铁和锌水平（=0.0001）高于患有子宫病变、卵巢无活性的母羊及对照组。卵巢无活性与母羊低硒水平以及山羊低硒和低锌水平相关（=0.05）。与对照组相比，患有雌激素主导型生殖障碍的母羊和山羊血清硒（=0.01）、铁（=0.03）和锌（=0.01）水平更高。与对照组相比，患有孕酮主导型生殖器官病变的母羊和山羊血清硒（=0.02）和锌（=0.05）水平更低。可以得出结论，生殖障碍与母羊和山羊血液中微量元素水平的变化有关。母羊和山羊血清中雌激素和孕酮水平与微量元素水平之间存在相互关系。
