Waktole Hika, Aden Mohammed, Ashenafi Hagos
Addis Ababa University, College of Veterinary Medicine and Agriculture, Department of Microbiology, Immunology and Veterinary Public Health, Bishoftu, Ethiopia.
Addis Ababa University, Aklilu Lemma Institute of Pathobiology, Animal Health and Zoonotic Diseases Research Unit, Addis Ababa, Ethiopia.
Vet Med Int. 2022 Mar 16;2022:6624293. doi: 10.1155/2022/6624293. eCollection 2022.
Brucellosis is an infectious disease in domestic and wild animals with serious zoonotic and economic implication in humans, being more severe in developing countries. The disease is highly prevalent in cattle, camels, and small ruminants in pastoral and agro-pastoral areas in Africa. Here we have investigated the seroepidemiology of camel brucellosis in and around Dire Dawa, eastern Ethiopia, using a cross-sectional study design to determine the seroprevalence of the disease and to identify risk factors that would facilitate the transmission of zoonotic diseases to humans. This study involved testing 350 serum samples from camels and interviewing 120 livestock owners. The modified Rose Bengal plate test (mRBPT) and the complement fixation test (CFT) were used as screening and confirmatory tests, respectively. The overall sero-prevalence of camel brucellosis was found to be 8.3% and 2% using mRBPT and CFT tests, respectively. Among the risk factors assessed, only abortion and body condition disclosed a statistically significant difference ( < 0.05) with regard to the seropositivity of camel brucellosis. Camel brucellosis is prevalent in eastern Ethiopia and there is a need to execute well-organized disease control and prevention programs and exercise public health education to scale up awareness of the community towards the disease.
布鲁氏菌病是一种家畜和野生动物的传染病，对人类具有严重的人畜共患病影响和经济影响，在发展中国家更为严重。该疾病在非洲牧区和农牧交错区的牛、骆驼和小反刍动物中高度流行。在此，我们采用横断面研究设计，对埃塞俄比亚东部德雷达瓦及其周边地区骆驼布鲁氏菌病的血清流行病学进行了调查，以确定该疾病的血清阳性率，并确定可能促进人畜共患病传播给人类的危险因素。本研究包括检测350份骆驼血清样本，并对120名牲畜所有者进行访谈。改良玫瑰红平板试验（mRBPT）和补体结合试验（CFT）分别用作筛查试验和确诊试验。使用mRBPT和CFT试验，骆驼布鲁氏菌病的总体血清阳性率分别为8.3%和2%。在所评估的危险因素中，只有流产和身体状况在骆驼布鲁氏菌病血清阳性方面显示出统计学上的显著差异（<0.05）。骆驼布鲁氏菌病在埃塞俄比亚东部流行，需要实施组织良好的疾病控制和预防计划，并开展公共卫生教育，以提高社区对该疾病的认识。
