Department of Chemistry, College of Natural Sciences, Jimma University, Jimma, Ethiopia.
Department of Physics, College of Natural and Computational Science, Dambi Dollo University, Ethiopia.
Luminescence. 2022 Jun;37(6):965-970. doi: 10.1002/bio.4241. Epub 2022 Apr 11.
A nickel oxide nanoparticle (NiO NP) composite with carbon dots (C-dots), (NiO NPs@C-dots) was synthesized, characterized, and then its antibacterial activity was evaluated. NiO NPs were prepared using Buddleja polystachya Fresen leaf extract and Ni(NO ) .6H O as precursors. The C-dots were synthesized from benzene-1,4-diamine and citric acid. The cubic structure of the NiO NPs and NiO NPs@C-dots was in phase with their average particle size distributions of 21.47 ± 0.56 and 21.61 ± 0.34 nm, respectively. The surface morphology of the NiO NPs@C-dots was characterized using field emission scanning electron microscopy and also revealed a large surface area, which is advantageous for the specified application. The X-ray diffraction result indicated a cubic face wurtzite structure and the crystalline nature of the NiO NPs. Carbon-doped compounds had no influence on the crystal structure of the NiO compound and no new peaks were observed. The antibacterial activity of a composite made up of NiO NPs@C-dots was tested, as well as the antibacterial activities of compounds produced against human photogenic bacterial strains. Both NiO NPs and NiO NPs@C-dots were found to be powerful against all bacterial strains, based on the bioassay results. NiO NPs and NiO@C-dots appeared to display strong to inhibitory effects of 14-20 mm and 17-23 mm, respectively.
采用苯-1,4-二胺和柠檬酸合成了碳点（C-dots），并与氧化镍纳米粒子（NiO NPs）复合，制备了 NiO NPs@C-dots 复合材料。NiO NPs 是用醉鱼草叶提取物和 Ni(NO3)2·6H2O 为前体制备的。C-dots 是由苯-1,4-二胺和柠檬酸合成的。NiO NPs 和 NiO NPs@C-dots 的立方结构与其平均粒径分布分别为 21.47 ± 0.56nm 和 21.61 ± 0.34nm 相对应。采用场发射扫描电子显微镜对 NiO NPs@C-dots 的表面形貌进行了表征，也揭示了其具有较大的比表面积，有利于特定的应用。X 射线衍射结果表明，NiO NPs 具有立方面闪锌矿结构和晶体性质。碳掺杂化合物对 NiO 化合物的晶体结构没有影响，没有观察到新的峰。测试了由 NiO NPs@C-dots 组成的复合材料的抗菌活性，以及化合物对人类光细菌菌株的抗菌活性。根据生物测定结果，发现 NiO NPs 和 NiO NPs@C-dots 对所有细菌菌株都具有很强的抗菌活性。NiO NPs 和 NiO@C-dots 分别表现出较强至抑制作用，抑菌圈直径为 14-20mm 和 17-23mm。
