Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM's NMIMS, Mumbai-56, Maharashtra, India.
Department of Pathology & Laboratory Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, K1P 1A5, Canada.
Pharm Pat Anal. 2022 Jan;11(1):23-32. doi: 10.4155/ppa-2021-0027. Epub 2022 Mar 29.
Baicalein is a medicinally important flavonoid present in , which has numerous biological benefits like anti-oxidant, anti-inflammatory, antihepatotoxicity, anticancer properties, etc. Recent studies have revealed that baicalein is an efficient antihepatoma agent and has the strongest antiproliferative effect toward cancerous bladder cell lines, and suppression of cell cycle progression in prostate cancer cells. This natural substance has a high commercial value because it strengthens the heart and cerebral vessels and protects the nervous system and also reduces diabetes and diabetic complications. In addition, baicalein is known to decrease inflammatory markers such as IL-1β, IL-6 and TNF-α. In this review, we have attempted to compile the list of recent therapeutic patents of baicalein used for treating different disorders.
黄芩素是一种具有重要医学意义的黄酮类化合物，存在于 中，具有许多生物益处，如抗氧化、抗炎、抗肝毒性、抗癌等。最近的研究表明，黄芩素是一种有效的肝癌治疗药物，对膀胱癌细胞系具有最强的抗增殖作用，并抑制前列腺癌细胞的细胞周期进展。这种天然物质具有很高的商业价值，因为它可以增强心脏和脑血管，保护神经系统，还可以降低糖尿病和糖尿病并发症的风险。此外，黄芩素还可以降低炎症标志物，如 IL-1β、IL-6 和 TNF-α。在这篇综述中，我们试图汇编了黄芩素治疗不同疾病的最新治疗专利列表。
