Eliska O, Elisková M, Mirejovský P
Nephron. 1986;44(2):136-41. doi: 10.1159/000184218.
Lymph vessels were evaluated in 20 transplanted canine kidneys. Prior to the occurrence of morphological rejection changes, transplants with good blood flow rates show areas with dilated but, less frequently, also undilated lymph vessels. In transplants with the presence of a rejection infiltrate and a decrease of the blood flow rate of 21-50% the lymph vessels may be focally dilated or, in contrast, narrowed by the cells of the rejection infiltrate. Numerous vesicles and vacuoles can be seen within the cytoplasm of endothelial cells. Interendothelial junctions may be occasionally open, the walls of endothelial cells become attenuated, and disintegration of the cell membrane is followed by a focal destruction of the wall and the development of defects. Cells of the rejection infiltrate penetrate through the gaps in the wall of the lymph vessels. The possible mechanism of the disintegration is discussed in this paper.
对20个移植的犬肾中的淋巴管进行了评估。在形态学排斥反应变化出现之前，血流速率良好的移植物显示出淋巴管扩张的区域，但也有较少见的未扩张的区域。在存在排斥浸润且血流速率降低21%-50%的移植物中，淋巴管可能局灶性扩张，或者相反，被排斥浸润细胞挤压而变窄。在内皮细胞的细胞质内可见大量小泡和空泡。内皮细胞间连接偶尔会开放，内皮细胞壁变薄，细胞膜解体后，会出现管壁的局灶性破坏和缺损。排斥浸润细胞通过淋巴管壁上的间隙穿透。本文讨论了这种解体的可能机制。
