一种新型生活质量问卷的验证：消化相关生活质量问卷（DQLQ）。
Validation of a novel quality of life questionnaire: the Digestion-associated Quality of Life Questionnaire (DQLQ).
机构信息
Food Science and Human Nutrition Department, University of Florida, 572 Newell Drive, PO Box 110370, Gainesville, FL, 32611-0370, USA.
出版信息
Health Qual Life Outcomes. 2022 Mar 28;20(1):53. doi: 10.1186/s12955-022-01956-4.
BACKGROUND
Few health-related quality of life (QOL) questionnaires are designed specifically for healthy populations and are specific to gastrointestinal (GI) symptoms even though healthy individuals may frequently experience gas, bloating, constipation, diarrhea, and abdominal pain. The purpose of this study was to develop and validate a tool that could assess the impact of GI symptoms on digestion-associated QOL in otherwise healthy individuals.
METHODS
After a review of current literature and with input from experienced GI researchers, a 24-item questionnaire was created. The questionnaire was reduced to 9 items with input from focus groups comprised of healthy adults experiencing GI-related symptoms and through variability analysis. The Digestion-associated QOL Questionnaire (DQLQ) was designed to be sensitive to the physical and mental well-being changes that may occur due to GI symptoms. The DQLQ was assessed for internal consistency reliability (Cronbach's alpha; McDonald's omega), test-retest reliability (intraclass correlation coefficient, ICC), and construct validity (Pearson correlations) in a study with healthy, academically stressed, undergraduate students. Convergent validity was evaluated by correlating the DQLQ with gastrointestinal symptom rating scale (GSRS) scores. Divergent validity was assessed by correlating DQLQ scores with stress scores, and bowel satisfaction scores.
RESULTS
A total of 594 students (age 18-30 years) completed the DQLQ. Internal consistency reliability was favorable (n = 594; α = 0.84, ω = 0.84). A high level of agreement and correlation between DQLQ scores was found with the test-retest reliability analysis (n = 273; ICC = 0.89). The questionnaire was shown to have good convergent validity through correlation with the GSRS (n = 594; r = 0.54). Divergent validity was also shown to be appropriate by correlating DQLQ scores with stress (n = 592; r = 0.13, p < 0.005), and bowel satisfaction (n = 592; r = 0.18, p < 0.001) scores.
CONCLUSION
The DQLQ is a reliable and valid questionnaire for assessing digestion-associated QOL in healthy individuals.
背景
很少有与健康相关的生活质量（QOL）问卷是专门为健康人群设计的，并且针对胃肠道（GI）症状具有特异性，尽管健康个体可能经常经历气体、腹胀、便秘、腹泻和腹痛。本研究的目的是开发和验证一种工具，以评估 GI 症状对健康个体消化相关生活质量的影响。
方法
在回顾现有文献并结合有经验的 GI 研究人员的意见后，创建了一个 24 项的问卷。通过对由经历 GI 相关症状的健康成年人组成的焦点小组的输入以及通过可变性分析，将问卷减少到 9 个项目。消化相关生活质量问卷（DQLQ）旨在敏感于由于 GI 症状可能发生的身体和心理健康变化。在一项针对健康、学业压力大的大学生的研究中，评估 DQLQ 的内部一致性可靠性（Cronbach 的 alpha；McDonald 的 omega）、重测信度（组内相关系数，ICC）和结构效度（Pearson 相关性）。通过与胃肠道症状评定量表（GSRS）评分相关联来评估收敛效度。通过与压力评分和肠道满意度评分相关联来评估发散效度。
结果
共有 594 名学生（年龄 18-30 岁）完成了 DQLQ。内部一致性可靠性良好（n=594；α=0.84，ω=0.84）。在 DQLQ 评分的重测信度分析中发现了高水平的一致性和相关性（n=273；ICC=0.89）。通过与 GSRS（n=594；r=0.54）相关联，显示出良好的收敛效度。通过与压力（n=592；r=0.13，p<0.005）和肠道满意度（n=592；r=0.18，p<0.001）评分相关联，显示出适当的发散效度。
结论
DQLQ 是一种可靠和有效的问卷，用于评估健康个体的消化相关生活质量。
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