Alvarez Melissa, Colee James, Langkamp-Henken Bobbi, Dahl Wendy J
Food Science and Human Nutrition Department, University of Florida, Gainesville, FL, United States.
Institute of Food and Agricultural Sciences (IFAS) Statistics, University of Florida, Gainesville, FL, United States.
Curr Dev Nutr. 2023 Jul 20;7(8):101976. doi: 10.1016/j.cdnut.2023.101976. eCollection 2023 Aug.
When examining gastrointestinal tolerance to nondigestible carbohydrates, a weekly vs. daily symptoms questionnaire may lessen participant burden. This secondary analysis examined the reliability and validity of the Gastrointestinal Symptom Rating Scale (GSRS) in healthy adults. The internal consistency reliability of the GSRS syndromes and a daily questionnaire (DQ) comparator were determined. The GSRS syndromes prediction of slow transit stool form was assessed by ROC analysis. The DQ ( = 0.76) and GSRS syndromes of constipation ( = 0.73; = 0.74), and diarrhea ( = 0.76; = 0.77) exhibited acceptable reliability, as did the GSRS overall ( = 0.76; = 0.87) but not the syndromes of abdominal pain ( = 0.54; = 0.54), reflux ( = 0.69; = 0.67), or indigestion ( = 0.64; = 0.67). The GSRS syndromes predicted slow transit stools (AUC = 0.855), and the GSRS items of stomach pain, nausea, flatus, constipation, and diarrhea were moderately correlated ( = 0.55-0.64; < 0.001) with the corresponding DQ items. The GSRS may be useful to assess gastrointestinal tolerance and efficacy of nondigestible carbohydrates given its performance at predicting slow transit stools, suggestive of constipation.
在检查胃肠道对不可消化碳水化合物的耐受性时，每周一次与每日一次的症状问卷可能会减轻参与者的负担。这项二次分析检验了胃肠道症状评定量表（GSRS）在健康成年人中的信度和效度。确定了GSRS综合征和每日问卷（DQ）比较器的内部一致性信度。通过ROC分析评估GSRS综合征对慢传输型大便形态的预测。DQ（=0.76）以及便秘（=0.73；=0.74）和腹泻（=0.76；=0.77）的GSRS综合征表现出可接受的信度，GSRS总体（=0.76；=0.87）也是如此，但腹痛（=0.54；=0.54）、反流（=0.69；=0.67）或消化不良（=0.64；=0.67）的综合征则不然。GSRS综合征预测了慢传输型大便（AUC = 0.855），并且胃痛、恶心、肠胃气胀、便秘和腹泻的GSRS条目与相应的DQ条目中度相关（=0.55 - 0.64；<0.001）。鉴于GSRS在预测慢传输型大便（提示便秘）方面的表现，它可能有助于评估不可消化碳水化合物的胃肠道耐受性和疗效。
