Key Laboratory of Biorheology Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, 400044, China.
Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Phys Eng Sci Med. 2022 Jun;45(2):475-485. doi: 10.1007/s13246-022-01112-8. Epub 2022 Mar 28.
Heart failure (HF) is a complex clinical syndrome that poses a major hazard to human health. Patients with different types of HF have great differences in pathogenesis and treatment options. Therefore, HF typing is of great significance for timely treatment of patients. In this paper, we proposed an automatic approach for HF typing based on heart sounds (HS) and convolutional recurrent neural networks, which provides a new non-invasive and convenient way for HF typing. Firstly, the collected HS signals were preprocessed with adaptive wavelet denoising. Then, the logistic regression based hidden semi-Markov model was utilized to segment HS frames. For the distinction between normal subjects and the HF patients with preserved ejection fraction or reduced ejection fraction, a model based on convolutional neural network and recurrent neural network was built. The model can automatically learn the spatial and temporal characteristics of HS signals. The results show that the proposed model achieved a superior performance with an accuracy of 97.64%. This study suggests the proposed method could be a useful tool for HF recognition and as a supplement for HF typing.
心力衰竭(HF)是一种复杂的临床综合征,对人类健康构成重大威胁。不同类型的 HF 患者在发病机制和治疗选择上存在很大差异。因此,HF 分型对患者的及时治疗具有重要意义。本文提出了一种基于心音(HS)和卷积递归神经网络的 HF 自动分型方法,为 HF 分型提供了一种新的非侵入性和便捷的方法。首先,对采集到的 HS 信号进行自适应小波去噪预处理。然后,利用基于逻辑回归的隐半马尔可夫模型对 HS 帧进行分割。对于射血分数保留型或射血分数降低型心力衰竭患者与正常受试者的区分,建立了基于卷积神经网络和递归神经网络的模型。该模型可以自动学习 HS 信号的时空特征。结果表明,所提出的模型具有 97.64%的优异性能。本研究表明,所提出的方法可能是一种有用的 HF 识别工具,并可作为 HF 分型的补充。