中性粒细胞/淋巴细胞比值在小儿复杂性阑尾炎中的敏感性和特异性。

Sensibilidad y especificidad del índice neutrófilo/linfocito en pacientes pediátricos con apendicitis aguda complicada.

机构信息

Servicio de Cirugía Pediátrica, Hospital General de Puebla "Eduardo Vazquez Navarro".

Servicio de Pediatría, Hospital General de Puebla "Eduardo Vazquez Navarro.

出版信息

Cir Cir. 2022;90(2):223-228. doi: 10.24875/CIRU.20001179.

DOI:10.24875/CIRU.20001179

PMID:35349558

Abstract

OBJECTIVE

Establish the sensibility and specificity of the neutrophil-lymphocyte rate (NLR) in pediatric patients with acute complicated appendicitis.

METHOD

Transversal, observational, descriptive, and retrospective study of pediatric patients between 4 to 16 years old with diagnosis of acute appendicitis, who had appendectomy, from December 2017 to January 2019. We calculated the NLR in every patient. To analyze the variables, we used the test of Mann-Whitney and we value the sensibility and specificity of the NLR.

RESULTS

There were 245 patients, 81 with simple appendicitis and 144 with complicated appendicitis. Just 27 of them were laparoscopic appendectomy. The NLR had a media of 10.48 in simple appendicitis, and 13.03 in complicated ones, with a p value of 0.02. the area under the curve was 0.622. There was a rate of 8.2 in complicated appendicitis to the NLR.

CONCLUSIONS

The NLR has been poorly studied in pediatric patients with acute appendicitis. In this study the NLR had a significant value in the patients with acute complicated appendicitis, with medium sensibility and a relatively low specificity.

摘要

目的

确定中性粒细胞与淋巴细胞比值（NLR）在儿科急性复杂性阑尾炎患者中的敏感性和特异性。

方法

这是一项回顾性、观察性、描述性的横断研究，研究对象为 2017 年 12 月至 2019 年 1 月期间，4 至 16 岁诊断为急性阑尾炎且接受阑尾切除术的儿科患者。我们计算了每位患者的 NLR。为了分析变量，我们使用了曼-惠特尼检验，并评估了 NLR 的敏感性和特异性。

结果

共有 245 例患者，81 例为单纯性阑尾炎，144 例为复杂性阑尾炎。其中只有 27 例接受了腹腔镜阑尾切除术。单纯性阑尾炎患者的 NLR 中位数为 10.48，复杂性阑尾炎患者的 NLR 中位数为 13.03，p 值为 0.02。曲线下面积为 0.622。复杂性阑尾炎患者的 NLR 发生率为 8.2%。