Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Department of Movement Sciences, College of Education, Health and Human Sciences, University of Idaho, Moscow, ID, USA.
Diabetes Metab J. 2022 Sep;46(5):747-755. doi: 10.4093/dmj.2021.0294. Epub 2022 Mar 30.
The weight-adjusted waist index (WWI) reflected body compositional changes with aging. This study was to investigate the association of WWI with abdominal fat and muscle mass in a diverse race/ethnic population.
Computed tomography (CT) data from 1,946 participants for abdominal fat and muscle areas from the Multi-Ethnic Study of Atherosclerosis (785 Whites, 252 Asians, 406 African American, and 503 Hispanics) were used. Among them, 595 participants underwent repeated CT. The WWI was calculated as waist circumference (cm) divided by the square root of body weight (kg). The associations of WWI with abdominal fat and muscle measures were examined, and longitudinal changes in abdominal composition measures were compared.
In all race/ethnic groups, WWI was positively correlated with total abdominal fat area (TFA), subcutaneous fat area, and visceral fat area, but negatively correlated with total abdominal muscle area (TMA) and abdominal muscle radiodensity (P<0.001 for all). WWI showed a linear increase with aging regardless of race and there were no significant differences in the WWI distribution between Whites, Asians, and African Americans. In longitudinal analyses, over 38.6 months of follow-up, all abdominal fat measures increased but muscle measures decreased, along with increase in WWI. The more the WWI increased, the more the TFA increased and the more the TMA decreased.
WWI showed positive associations with abdominal fat mass and negative associations with abdominal muscle mass, which likely reflects the abdominal compositional changes with aging in a multi-ethnic population.
体重调整腰围指数（WWI）反映了随着年龄增长身体成分的变化。本研究旨在探讨 WWI 与不同种族/族裔人群腹部脂肪和肌肉量的关系。
使用来自动脉粥样硬化多民族研究（785 名白人、252 名亚洲人、406 名非裔美国人、503 名西班牙裔人）的 1946 名参与者的计算机断层扫描（CT）数据来测量腹部脂肪和肌肉面积。其中，595 名参与者接受了重复 CT 检查。WWI 计算为腰围（cm）除以体重的平方根（kg）。研究了 WWI 与腹部脂肪和肌肉测量指标的相关性，并比较了腹部成分测量指标的纵向变化。
在所有种族/族裔群体中，WWI 与总腹部脂肪面积（TFA）、皮下脂肪面积和内脏脂肪面积呈正相关，与总腹部肌肉面积（TMA）和腹部肌肉密度呈负相关（P<0.001）。无论种族如何，WWI 都随着年龄的增长呈线性增加，并且在白种人、亚洲人和非裔美国人之间，WWI 的分布没有显著差异。在纵向分析中，经过 38.6 个月的随访，所有腹部脂肪测量值均增加，而肌肉测量值均减少，同时 WWI 增加。随着 WWI 的增加，TFA 增加越多，TMA 减少越多。
WWI 与腹部脂肪量呈正相关，与腹部肌肉量呈负相关，这可能反映了多民族人群中随着年龄增长腹部成分的变化。
