School of Stomatology, Hangzhou Normal University, Hangzhou, Zhejiang, China.
The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Front Public Health. 2024 Jul 26;12:1429244. doi: 10.3389/fpubh.2024.1429244. eCollection 2024.
The relationship between the weight-adjusted-waist index (WWI) and grip strength, a crucial marker in assessing sarcopenia, lacks clarity. We aimed to explore the relationship between WWI and muscle strength across genders.
The cross-sectional study involved adults with complete data on WWI and grip strength from the 2011-2014 National Health and Nutrition Examination Survey. WWI was derived by dividing waist circumference by the square root of weight. Weighted multivariable logistic regression and smooth curve fitting techniques were used to examine the independent association and potential non-linear relationship between WWI and grip strength. A two-piecewise linear regression model was utilized to determine the threshold effect. Additionally, subgroup analyses and interaction tests were conducted.
The study encompassed 9,365 participants, including 4,661 males and 4,704 females. Multivariate logistic regression analysis revealed a negative correlation between WWI and grip strength among males ( = -11.49, 95% CI: -12.38, -10.60, < 0.001) as well as females ( = -2.53, 95% CI: -2.98, -2.08, < 0.001). Subgroup analysis showed that the negative correlation of WWI with grip strength remained consistent across various age groups and levels of obesity for both males and females.
An increase in WWI correlates with reduced muscle strength in both males and females. WWI was negatively associated not only with muscle mass but also with muscle strength. WWI may serve as an assessment tool for sarcopenia, but further large-scale studies are needed to clarify causality.
体重调整腰围指数（WWI）与握力之间的关系，握力是评估肌肉减少症的关键指标之一，但目前两者之间的关系尚不清楚。本研究旨在探讨性别间 WWI 与肌肉力量之间的关系。
本横断面研究纳入了 2011-2014 年全国健康和营养调查中具有完整 WWI 和握力数据的成年人。通过将腰围除以体重的平方根来计算 WWI。采用加权多变量逻辑回归和平滑曲线拟合技术来检验 WWI 与握力之间的独立关联和潜在非线性关系。采用两段线性回归模型来确定阈值效应。此外，还进行了亚组分析和交互检验。
该研究共纳入 9365 名参与者，其中男性 4661 名，女性 4704 名。多变量逻辑回归分析显示，男性（ = -11.49，95%CI：-12.38，-10.60， < 0.001）和女性（ = -2.53，95%CI：-2.98，-2.08， < 0.001）的 WWI 与握力呈负相关。亚组分析显示，男性和女性的 WWI 与握力的负相关性在不同年龄组和肥胖水平中均保持一致。
WWI 的增加与男性和女性的肌肉力量下降相关。WWI 不仅与肌肉质量有关，还与肌肉力量有关。WWI 可作为评估肌肉减少症的工具，但需要进一步的大规模研究来明确其因果关系。
