Department of Neonatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2022 Mar 15;24(3):332-338. doi: 10.7499/j.issn.1008-8830.2111002.
The perinatal period is the key period for the development of brain and central nervous system, and different events in this period will have a profound influence on brain development. Glucocorticoids, antibiotics, magnesium sulfate, caffeine, pulmonary surfactant, and mild hypothermia treatment are commonly used drugs or treatment methods in the perinatal period and are closely associated with the prognosis of neonatal neurodevelopment. This article reviews the latest research on the effect of perinatal treatments on neonatal neurodevelopment, so as to provide a reference for clinical decision making.
围产期是大脑和中枢神经系统发育的关键时期,这一时期的不同事件都会对大脑发育产生深远影响。围产期常用的药物或治疗方法有糖皮质激素、抗生素、硫酸镁、咖啡因、肺表面活性剂、亚低温治疗等,这些方法均与新生儿神经发育预后密切相关。本文就围产期治疗对新生儿神经发育的影响的最新研究作一综述,以期为临床决策提供参考。