Centre for Trials Research, Cardiff University, Cardiff, UK
Bristol Centre for Surgical Research, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
RMD Open. 2022 Mar;8(1). doi: 10.1136/rmdopen-2021-002093.
The current standard of care in rheumatoid arthritis (RA) requires regular assessment of disease activity (DA). All standard RA DA measurement instruments require joint counts to be undertaken by a healthcare professional with/without a blood test. Few healthcare providers have the capacity to assess patients as frequently as stipulated by guidelines. Patient Reported Outcome Measures (PROMs) could be an efficient and informative way to assess RA DA, which is highlighted by the SARS-COV-2 pandemic, as most consultations are remote rather than face-to-face. We aimed to assess all PROMs for RA DA against the internationally recognised COSMIN guidelines to provide evidence-based recommendations to select the most suitable PROMs.
Review registered on PROSPERO as CRD42020176176. The search strategy was based on a previous similar systematic review and expanded to include all articles up to January 2019. All identified articles were rated by two independent assessors following the COSMIN guidelines.
668 abstracts were identified, with 10 articles included. A further 21 were identified from a previous review. Ten PROMs were identified. There was insufficient evidence to place any of the identified PROMs into recommendation for use category A due to lack of evidence for content validity, as stipulated by the COSMIN guidelines.
Lack of evidence of content validity limits suitable PROM selection, therefore none can be recommended for use. It is acknowledged that all included PROMs were developed before the COSMIN guidelines were published. Future research on PROMs for RA DA must provide evidence of content validity.
类风湿关节炎 (RA) 的当前治疗标准需要定期评估疾病活动度 (DA)。所有标准的 RA DA 测量仪器都需要由医疗保健专业人员进行关节计数，无论是否进行血液检查。很少有医疗保健提供者有能力按照指南规定的频率评估患者。患者报告的结果测量 (PROMs) 可能是评估 RA DA 的一种有效且信息丰富的方法，这在 SARS-COV-2 大流行中得到了强调，因为大多数咨询都是远程的而不是面对面的。我们旨在根据国际认可的 COSMIN 指南评估所有 RA DA 的 PROMs，为选择最合适的 PROMs 提供循证建议。
在 PROSPERO 上注册的综述，编号为 CRD42020176176。搜索策略基于以前的类似系统评价，并扩展到包括截至 2019 年 1 月的所有文章。所有确定的文章均按照 COSMIN 指南由两名独立评估者进行评估。
共确定了 668 篇摘要，其中有 10 篇文章被纳入。从以前的综述中又确定了 21 篇。确定了 10 种 PROMs。由于缺乏 COSMIN 指南规定的内容有效性证据，没有任何一种已确定的 PROM 可以被归入使用推荐类别 A。
缺乏内容有效性的证据限制了合适 PROM 的选择，因此没有一种可以推荐使用。需要承认的是，所有纳入的 PROM 都是在 COSMIN 指南发布之前开发的。未来针对 RA DA 的 PROM 研究必须提供内容有效性的证据。
