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神经认知老化数据发布,包含行为、结构和多回波功能 MRI 测量结果。

Neurocognitive aging data release with behavioral, structural and multi-echo functional MRI measures.

机构信息

Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada.

McConnell Brain Imaging Centre, McGill University, Montreal, QC, Canada.

出版信息

Sci Data. 2022 Mar 29;9(1):119. doi: 10.1038/s41597-022-01231-7.

Abstract

Central to understanding human behavior is a comprehensive mapping of brain-behavior relations within the context of lifespan development. Reproducible discoveries depend upon well-powered samples of reliable data. We provide to the scientific community two, 10-minute, multi-echo functional MRI (ME-fMRI) runs, and structural MRI (T1-MPRAGE), from 181 healthy younger (ages 18-34 y) and 120 older adults (ages 60-89 y). T2-FLAIR MRIs and behavioral assessments are available in a majority subset of over 250 participants. Behavioral assessments include fluid and crystallized cognition, self-reported measures of personality, and socioemotional functioning. Initial quality control and validation of these data is provided. This dataset will be of value to scientists interested in BOLD signal specifically isolated from ME-fMRI, individual differences in brain-behavioral associations, and cross-sectional aging effects in healthy adults. Demographic and behavioral data are available within the Open Science Framework project "Goal-Directed Cognition in Older and Younger Adults" ( http://osf.io/yhzxe/ ), which will be augmented over time; neuroimaging data are available on OpenNeuro ( https://openneuro.org/datasets/ds003592 ).

摘要

理解人类行为的核心是在生命发展过程中全面绘制大脑-行为关系图。可重复的发现取决于具有可靠数据的强大样本。我们向科学界提供了 181 名健康年轻(18-34 岁)和 120 名老年人(60-89 岁)的两个 10 分钟多回波功能磁共振成像(ME-fMRI)和结构磁共振成像(T1-MPRAGE)。超过 250 名参与者的大多数都提供 T2-FLAIR MRI 和行为评估。行为评估包括流体和晶体认知、人格的自我报告测量以及社会情感功能。这些数据的初始质量控制和验证已经提供。对于那些对 ME-fMRI 中特定的 BOLD 信号、大脑-行为关联的个体差异以及健康成年人的横断面老化效应感兴趣的科学家来说,这个数据集将具有重要价值。人口统计学和行为数据可在开放科学框架项目“老年和年轻成年人的目标导向认知”(http://osf.io/yhzxe/)中获得,该项目将随着时间的推移不断增加;神经影像学数据可在 OpenNeuro(https://openneuro.org/datasets/ds003592)上获得。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00c/8964687/7cb339e7f0cb/41597_2022_1231_Fig1_HTML.jpg

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