Hardy Krista, Kwok Karen, Bouchard Danielle R, Bharti Neha, Gamey Dean, Vergis Ashley
Surgery, University of Manitoba, Winnipeg, CAN.
Kinesiology, University of New Brunswick, Fredericton, CAN.
Cureus. 2022 Feb 24;14(2):e22566. doi: 10.7759/cureus.22566. eCollection 2022 Feb.
Background Evidence supports the association between exercise and outcomes following bariatric surgery. However, there is a lack of knowledge regarding the short-term benefits of preoperative exercise. Objectives The objective of this pilot study was to evaluate the feasibility and functional benefits of a 12-week preoperative exercise program in patients awaiting bariatric surgery. The primary aim was the six-minute walk test (6MWT). The secondary aim of this study included anthropometric measures, strength, and quality of life. Methods A total of 54 patients were enrolled in this pilot randomized controlled study. Of them, 29 patients received standard multidisciplinary preoperative care, while 25 patients participated in a 12-week supervised exercise program in addition to standard preoperative care consisting of strength and aerobic exercises three times per week in a fitness facility. The primary outcome was improvement in 6MWT. Secondary outcomes included other functional outcomes, quality of life, and anthropometric measures. Results Average attendance for the intervention group was 27.2 (75.6%) of 36 sessions. There was a mean improvement of 27 ± 10 meters in the intervention group compared with a reduction of 5 ± 10 meters in the control group (p = 0.003). Patients in the intervention group had significant improvement in all self-reported quality-of-life domains, particularly in the variables related to symptoms, hygiene, and emotions. Conclusions A 12-week preoperative exercise intervention was feasible and showed association with a statistically significant improvement in 6MWT and quality-of-life measures in patients awaiting bariatric surgery. The results of this study will inform sample size calculations and recruitment planning for a future study that will assess the longer-term benefits of a pre-surgical fitness intervention.
背景 证据支持减肥手术后运动与预后之间的关联。然而,对于术前运动的短期益处尚缺乏了解。目的 本试点研究的目的是评估一项为期12周的术前运动计划对等待减肥手术患者的可行性和功能益处。主要目标是六分钟步行试验(6MWT)。本研究的次要目标包括人体测量指标、力量和生活质量。方法 共有54例患者纳入了这项试点随机对照研究。其中,29例患者接受标准的多学科术前护理,而25例患者除接受标准术前护理外,还参加了一项为期12周的有监督的运动计划,该计划包括在健身设施中每周进行三次力量和有氧运动。主要结局是6MWT的改善。次要结局包括其他功能结局、生活质量和人体测量指标。结果 干预组的平均出勤次数为36节课程中的27.2节(75.6%)。干预组平均提高了27±10米,而对照组减少了5±10米(p = 0.003)。干预组患者在所有自我报告的生活质量领域均有显著改善,尤其是在与症状、卫生和情绪相关的变量方面。结论 一项为期12周的术前运动干预是可行的,并且显示出与等待减肥手术患者的6MWT和生活质量测量值在统计学上的显著改善相关。本研究结果将为未来评估术前健身干预长期益处的研究的样本量计算和招募计划提供信息。