Allendorf Valerie, Denzin Nicolai, Conraths Franz J, Boden Lisa A, Elvinger François, Magouras Ioannis, Stegeman Arjan, Wood James L N, Urueña Ana Carvajal, Grace Katherine E F, Stärk Katharina D C
Friedrich-Loeffler-Institut, Institute of Epidemiology, Greifswald - Insel Riems, Germany.
Friedrich-Loeffler-Institut, Institute of International Animal Health & One Health, Greifswald - Insel Riems, Germany.
One Health. 2022 Jun;14:100381. doi: 10.1016/j.onehlt.2022.100381. Epub 2022 Mar 25.
Due to the zoonotic origin of SARS-Coronavirus 2 (SARS-CoV-2), the potential for its transmission from humans back to animals and the possibility that it might establish ongoing infection pathways in other animal species has been discussed. Cats are highly susceptible to SARS-CoV-2 and were shown experimentally to transmit the virus to other cats. Infection of cats has been widely reported. Domestic cats in COVID-19-positive households could therefore be a part of a human to animal to human transmission pathway. Here, we report the results of a qualitative risk assessment focusing on the potential of cat to human transmission in such settings. The assessment was based on evidence available by October 2021. After the introduction of SARS-CoV-2 to a household by a human, cats may become infected and infected cats may pose an additional infection risk for other members of the household. In order to assess this additional risk qualitatively, expert opinion was elicited within the framework of a modified Delphi procedure. The conclusion was that the additional risk of infection of an additional person in a household associated with keeping a domestic cat is very low to negligible, depending on the intensity of cat-to-human interactions. The separation of cats from humans suffering from SARS-CoV-2 infection should contribute to preventing further transmission.
由于严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的人畜共患起源，人们已经讨论了其从人类反向传播回动物的可能性，以及它可能在其他动物物种中建立持续感染途径的可能性。猫对SARS-CoV-2高度易感，并且实验表明其可将病毒传播给其他猫。猫感染的情况已有广泛报道。因此，新冠病毒检测呈阳性家庭中的家猫可能成为人传动物再传人的传播途径的一部分。在此，我们报告一项定性风险评估的结果，该评估聚焦于在此类情况下猫传人的可能性。评估基于截至2021年10月可得的证据。人类将SARS-CoV-2引入家庭后，猫可能会被感染，而感染的猫可能会给家庭中的其他成员带来额外的感染风险。为了定性评估这一额外风险，在改良德尔菲法的框架内征求了专家意见。结论是，与饲养家猫相关的家庭中额外一人感染的额外风险非常低至可忽略不计，这取决于猫与人互动的强度。将猫与感染SARS-CoV-2的人隔离开来应有助于防止进一步传播。
