玻璃体视网膜淋巴瘤的出血性肿块样表现
Hemorrhagic Mass-Like Presentation of Vitreoretinal Lymphoma.
作者信息
Marchese Alessandro, Cicinelli Maria Vittoria, Bandello Francesco, Modorati Giulio, Miserocchi Elisabetta
机构信息
Department of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
出版信息
Ocul Oncol Pathol. 2022 Feb;8(1):9-15. doi: 10.1159/000519300. Epub 2021 Sep 22.
PURPOSE
The aim of this study was to report the presentation, treatment, and outcomes of vitreoretinal lymphoma (VRL) associated with hemorrhagic mass-like lesions (HMLs) in the retina.
METHODS
This study was a retrospective analysis of patients with HMLs associated with VRL seen at a single tertiary referral center. For each patient, the clinical charts, the fundus imaging, and the treatment outcomes were reviewed.
RESULTS
Three eyes of 2 patients had VRL with HMLs. In all study eyes, HMLs were preceded by an area of retinitis-like retinal infiltration and evolved into elevated hemorrhagic masses. Two eyes had multiple relapses with HMLs. All HMLs regressed with treatment and were replaced by extensive chorioretinal atrophy.
CONCLUSION
VRL can present with HMLs. HMLs seem to correspond to massive intraretinal infiltration by VRL, mimicking a solid mass. Despite response to therapy, HMLs are associated with poor anatomical and functional outcomes.
目的
本研究旨在报告视网膜玻璃体视网膜淋巴瘤（VRL）合并视网膜出血性肿块样病变（HMLs）的临床表现、治疗及预后。
方法
本研究是对在一家三级转诊中心就诊的合并VRL的HMLs患者进行的回顾性分析。对每位患者的临床病历、眼底成像及治疗结果进行了回顾。
结果
2例患者的3只眼患有合并HMLs的VRL。在所有研究眼中，HMLs之前均有视网膜样视网膜浸润区域，并发展为隆起的出血性肿块。2只眼出现HMLs多次复发。所有HMLs经治疗后消退，并被广泛的脉络膜视网膜萎缩所取代。
结论
VRL可伴有HMLs。HMLs似乎对应于VRL在视网膜内的大量浸润，类似实体肿块。尽管对治疗有反应，但HMLs与不良的解剖和功能预后相关。
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