Sutanto Clarinda Nataria, Loh Wen Wei, Toh Darel Wee Kiat, Lee Delia Pei Shan, Kim Jung Eun
Department of Food Science and Technology, Faculty of Science, National University of Singapore, Singapore, Singapore.
Front Nutr. 2022 Mar 9;9:832341. doi: 10.3389/fnut.2022.832341. eCollection 2022.
Poor sleep has been associated with the increased risk of developing detrimental health conditions. Diet and certain nutrients, such as dietary protein (PRO) may improve sleep. This cross-sectional study aimed to investigate the relationship between PRO intake, their amino acid components, and sources with sleep quality in middle-aged and older adults residing in Singapore. A dataset of 104 healthy subjects between the age of 50 and 75 years old were used. Collected data included 3-day food record and sleep quality [sleep duration, global sleep score (GSS), sleep latency (SL), and sleep efficiency (SE)]. The collected 3-day food records were extracted for PRO, tryptophan (Trp), and large neutral amino acid (LNAA) intake. PRO intake was further categorized into plant and animal PRO. A multivariate multiple linear regression (MLR) was performed to assess the association between PRO intake and sleep quality. Dietary Trp:LNAA ratio was positively associated with sleep duration (β: 108.234 h; : 0.005) after multiple covariates adjustment. Similarly, plant Trp (β: 2.653 h/g; : 0.020) and plant Trp:LNAA (β: 54.006 h; : 0.008) was positively associated with sleep duration. No significant associations were observed for both SL and SE. Sleep duration in middle-aged and older Singaporean adults was positively associated with dietary Trp and Trp:LNAA, especially when obtained from plant sources.
睡眠质量差与患有害健康状况的风险增加有关。饮食和某些营养素，如膳食蛋白质（PRO）可能会改善睡眠。这项横断面研究旨在调查居住在新加坡的中老年人的PRO摄入量、其氨基酸成分和来源与睡眠质量之间的关系。使用了一个包含104名年龄在50至75岁之间的健康受试者的数据集。收集的数据包括3天的食物记录和睡眠质量[睡眠时间、整体睡眠评分（GSS）、睡眠潜伏期（SL）和睡眠效率（SE）]。从收集的3天食物记录中提取PRO、色氨酸（Trp）和大中性氨基酸（LNAA）的摄入量。PRO摄入量进一步分为植物性和动物性PRO。进行了多元多重线性回归（MLR）以评估PRO摄入量与睡眠质量之间的关联。在对多个协变量进行调整后，膳食Trp:LNAA比值与睡眠时间呈正相关（β：108.234小时；P：0.005）。同样，植物性Trp（β：2.653小时/克；P：0.020）和植物性Trp:LNAA（β：54.006小时；P：0.008）与睡眠时间呈正相关。未观察到SL和SE有显著关联。新加坡中老年人的睡眠时间与膳食Trp和Trp:LNAA呈正相关，尤其是从植物来源获取时。
