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19至59岁成年人的乙型肝炎普遍疫苗接种:美国免疫实践咨询委员会2022年更新建议

Universal Hepatitis B Vaccination in Adults Aged 19-59 Years: Updated Recommendations of the Advisory Committee on Immunization Practices - United States, 2022.

作者信息

Weng Mark K, Doshani Mona, Khan Mohammed A, Frey Sharon, Ault Kevin, Moore Kelly L, Hall Eric W, Morgan Rebecca L, Campos-Outcalt Doug, Wester Carolyn, Nelson Noele P

出版信息

MMWR Morb Mortal Wkly Rep. 2022 Apr 1;71(13):477-483. doi: 10.15585/mmwr.mm7113a1.

Abstract

Hepatitis B (HepB) vaccines have demonstrated safety, immunogenicity, and efficacy during the past 4 decades (1,2). However, vaccination coverage among adults has been suboptimal, limiting further reduction in hepatitis B virus (HBV) infections in the United States. This Advisory Committee on Immunization Practices (ACIP) recommendation expands the indicated age range for universal HepB vaccination to now include adults aged 19-59 years. Removing the risk factor assessment previously recommended to determine vaccine eligibility in this adult age group (2) could increase vaccination coverage and decrease hepatitis B cases.

摘要

在过去40年里,乙型肝炎(乙肝)疫苗已证明了其安全性、免疫原性和有效性(1,2)。然而,成人中的疫苗接种覆盖率一直未达到最佳水平,限制了美国乙型肝炎病毒(HBV)感染率的进一步降低。免疫实践咨询委员会(ACIP)的这项建议扩大了普遍接种乙肝疫苗的指定年龄范围,现在包括19至59岁的成年人。取消此前建议用于确定该成年年龄组疫苗接种资格的风险因素评估(2)可能会提高疫苗接种覆盖率并减少乙肝病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3e2/8979596/0f896b6d43a2/mm7113a1-F.jpg

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