Li Ling-Xu, Lv Ying-Jun, Guo Qing-Yong, Liao Yun, Guo Yi-Wen, Su Ze-Nan, Yao Da-Wei, Yang De-Ji
Diagnostic Imaging Center of Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi, China.
Front Vet Sci. 2022 Mar 11;9:810977. doi: 10.3389/fvets.2022.810977. eCollection 2022.
The aim of this study was to describe radiography, computed tomography (CT), and magnetic resonance imaging (MRI) findings of enzootic nasal tumors in goats infected with enzootic nasal tumor viruses. Five of six goats with a mean age of 2 years, showed clinical signs of respiratory disease. Head radiographs showed increased density of the unilateral or bilateral nasal cavity in four goats, and a CT scan showed that the space-occupying lesion of the nasal cavity originated from the ethmoid bone and was enhanced homogeneously postcontrast in all goats. The nasal concha was destroyed and the paranasal sinus mucosa was thickened and filled with fluid in some goats. On MRI, the mass exhibited equal or slightly higher signal intensity on T2 weighted images, equal signal intensity on T1 weighted images, a high signal on fluid-attenuated inversion recovery images and heterogeneous enhancement postcontrast. After dissection, histopathological examination of the mass and virus genome detection of the nasal secretions confirmed that the intranasal mass was a low-grade adenocarcinoma and that the goats were infected with enzootic nasal tumor virus type 2. In conclusion, CT and MRI have high diagnostic values for enzootic nasal tumors because they match the postmortem findings and are more accurate than radiography.
本研究的目的是描述感染地方性鼻肿瘤病毒的山羊的地方性鼻肿瘤的X线摄影、计算机断层扫描（CT）和磁共振成像（MRI）表现。六只平均年龄为2岁的山羊中有五只出现了呼吸道疾病的临床症状。头部X线片显示四只山羊单侧或双侧鼻腔密度增加，CT扫描显示鼻腔占位性病变起源于筛骨，所有山羊造影后均呈均匀强化。部分山羊鼻甲被破坏，鼻窦黏膜增厚并充满液体。在MRI上，肿块在T2加权图像上表现为等信号或略高信号，在T1加权图像上表现为等信号，在液体衰减反转恢复图像上表现为高信号，造影后呈不均匀强化。解剖后，对肿块进行组织病理学检查并对鼻腔分泌物进行病毒基因组检测，证实鼻腔内肿块为低级别腺癌，且山羊感染了2型地方性鼻肿瘤病毒。总之，CT和MRI对地方性鼻肿瘤具有较高的诊断价值，因为它们与尸检结果相符，且比X线摄影更准确。
