Wang Shu, Li JianNa, Cao Yihong, Gu JingWei, Wang YuanFeng, Chen ShiGuo
Nanshan District Key Lab for Biopolymers and Safety Evaluation, Shenzhen Key Laboratory of Polymer Science and Technology, Guangdong Research Center for Interfacial Engineering of Functional Materials, College of Materials Science and Engineering, Shenzhen University, Shenzhen, 518060 People's Republic of China.
Department of Pathogen Biology, School of Basic Medical Sciences, Shenzhen University Health Sciences Center, Shenzhen, 518060 People's Republic of China.
Adv Fiber Mater. 2022;4(1):119-128. doi: 10.1007/s42765-021-00100-z. Epub 2021 Sep 20.
Pathogenic bacteria can proliferate rapidly on porous fabrics to form bacterial plaques/biofilms, resulting in potential sources of cross-transmissions of diseases and increasing cross-infection in public environments. Many works on antibacterial modification of cotton fabrics have been reported, while very few works were reported to endow poly(ethylene terephthalate) (PET) fabrics with non-leaching antibacterial function without compromising their innate physicochemical properties though PET is the most widely used fabric. Therefore, it is urgent to impart the PET fabrics with non-leaching antibacterial activity. Herein, a novel halamine compound, 1-chloro-3-benzophenone-5,5-dimethylhydantoin (Cl-BPDMH), was developed to be covalently bonded onto PET fabrics, rendering non-leaching antibacterial activity while negligible cytotoxicity based on contact-killing principle. Bacterial was easily adhered to Cl-BPDMH finished PET fabrics, and then it was inactivated quickly within 10 s. Furthermore, the breaking strength, breaking elongation, tearing strength, water vapor permeability, air permeability and whiteness of Cl-BPDMH finished PET fabrics were improved obviously compared to raw PET fabrics. Hence, this work developed a facile approach to fabricate multifunctional synthetic textiles to render outstanding and rapid bactericidal activity without compromising their physicochemical properties and biocompatibility.
The online version contains supplementary material available at 10.1007/s42765-021-00100-z.
致病细菌可在多孔织物上迅速繁殖，形成菌斑/生物膜，成为疾病交叉传播的潜在来源，并增加公共环境中的交叉感染。关于棉织物抗菌改性的研究已有很多报道，然而，尽管聚对苯二甲酸乙二酯（PET）是使用最广泛的织物，但赋予PET织物非浸出性抗菌功能且不损害其固有物理化学性质的研究却很少。因此，迫切需要赋予PET织物非浸出性抗菌活性。在此，一种新型卤胺化合物1-氯-3-二苯甲酮-5,5-二甲基乙内酰脲（Cl-BPDMH）被开发出来，通过共价键合到PET织物上，基于接触杀灭原理赋予其非浸出性抗菌活性，同时细胞毒性可忽略不计。细菌很容易附着在Cl-BPDMH整理的PET织物上，并在10秒内迅速失活。此外，与原始PET织物相比，Cl-BPDMH整理的PET织物的断裂强度、断裂伸长率、撕裂强度、水蒸气透过率、透气率和白度都有明显提高。因此，这项工作开发了一种简便的方法来制造多功能合成纺织品，使其具有出色的快速杀菌活性，同时不损害其物理化学性质和生物相容性。
在线版本包含可在10.1007/s42765-021-00100-z获取的补充材料。
