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术前使用聚维酮碘。一项前瞻性随机研究。

Preoperative use of povidone-iodine. A prospective, randomized study.

作者信息

Zdeblick T A, Lederman M M, Jacobs M R, Marcus R E

出版信息

Clin Orthop Relat Res. 1986 Dec(213):211-5.

PMID:3536248
Abstract

One hundred one adult orthopedic surgical patients were studied in a randomized, prospective clinical trial to compare the effectiveness of the standard povidone-iodine scrub and paint with povidone-iodine painting alone for presurgical skin preparation. No infections occurred in either group. The scrub-plus-paint group showed a 0.601 logarithmic reduction in bacteria counts, compared with 0.622 with painting alone. Further, 36.8% of the patients in the scrub-plus-paint group had skin counts that actually increased after preparation, compared with 13.8% of patients in the paint-only group. The preparation bacterial counts among inpatients, who received preoperative hexachlorophene showers, were significantly lower than that of outpatients, who did not receive preoperative showers. The data support the use of the preoperative hexachlorophene shower and the omission of scrubbing from the surgical skin preparation technique.

摘要

在一项随机、前瞻性临床试验中,对101名成年骨科手术患者进行了研究,以比较标准聚维酮碘擦洗加涂抹与仅用聚维酮碘涂抹进行术前皮肤准备的效果。两组均未发生感染。擦洗加涂抹组的细菌计数对数减少了0.601,而仅涂抹组为0.622。此外,擦洗加涂抹组中有36.8%的患者在准备后皮肤细菌计数实际上增加了,而仅涂抹组为13.8%。接受术前六氯酚沐浴的住院患者的术前准备细菌计数显著低于未接受术前沐浴的门诊患者。这些数据支持术前使用六氯酚沐浴,并在手术皮肤准备技术中省略擦洗步骤。

相似文献

1
Preoperative use of povidone-iodine. A prospective, randomized study.术前使用聚维酮碘。一项前瞻性随机研究。
Clin Orthop Relat Res. 1986 Dec(213):211-5.
2
Paint-only is equivalent to scrub-and-paint in preoperative preparation of abdominal surgery sites.在腹部手术部位的术前准备中,仅涂擦法与擦洗加涂擦法效果相当。
J Am Coll Surg. 2005 Nov;201(5):737-41. doi: 10.1016/j.jamcollsurg.2005.05.023. Epub 2005 Aug 31.
3
Comparison of surgical wound infection after preoperative skin preparation with 4% chlorhexidine [correction of chlohexidine] and povidone iodine: a prospective randomized trial.术前使用4%氯己定[纠正:洗必泰]与聚维酮碘进行皮肤准备后手术伤口感染的比较:一项前瞻性随机试验。
J Med Assoc Thai. 2009 Jul;92(7):898-902.
4
Povidone-iodine irrigation of the subcutaneous tissue to prevent surgical wound infections.皮下组织聚维酮碘冲洗预防手术伤口感染。
Surg Gynecol Obstet. 1982 Aug;155(2):221-4.
5
The effect of povidone-iodine solutions used as surgical preparations on the bacterial flora of the skin.用作手术准备的聚维酮碘溶液对皮肤细菌菌群的影响。
Adv Ther. 1990 Jan-Feb;7(1):1-8.
6
Preoperative skin preparation and intraoperative pelvic irrigation: impact on post-cesarean endometritis and wound infection.术前皮肤准备及术中盆腔冲洗:对剖宫产术后子宫内膜炎及伤口感染的影响
Obstet Gynecol. 1993 Jun;81(6):922-5.
7
Efficacy of povidone-iodine in preputial antisepsis.聚维酮碘在包皮消毒中的疗效。
Int J Clin Pract. 2003 Nov;57(9):752-4.
8
The effect of povidone-iodine on postoperative wound infection in abdominal surgery.聚维酮碘对腹部手术术后伤口感染的影响。
Neth J Surg. 1981 Oct;33(4):186-9.
9
A comparative study of surgical skin preparation methods.手术皮肤准备方法的比较研究
Surg Gynecol Obstet. 1983 Sep;157(3):265-8.
10
Povidone-iodine wound irrigation and wound sepsis.聚维酮碘伤口冲洗与伤口脓毒症
Surg Gynecol Obstet. 1983 Nov;157(5):426-30.

引用本文的文献

1
Surgical Site Preparation Using Alcohol with Chlorhexidine Compared with Povidone Iodine with Chlorhexidine Results in Similar Rate of Infection After Primary Total Joint Arthroplasty.与使用聚维酮碘加氯己定相比,使用酒精加氯己定进行手术部位准备,在初次全关节置换术后的感染率相似。
Antibiotics (Basel). 2025 Feb 5;14(2):155. doi: 10.3390/antibiotics14020155.
2
No Clear Benefit of Chlorhexidine Use at Home Before Surgical Preparation.在家中手术准备前使用洗必泰无明显益处。
J Am Acad Orthop Surg. 2018 Jan 15;26(2):e39-e47. doi: 10.5435/JAAOS-D-16-00866.
3
Antibiotics and antiseptics for preventing infection in people receiving revision total hip and knee prostheses: a systematic review of randomized controlled trials.
用于预防接受髋关节和膝关节翻修假体患者感染的抗生素和防腐剂:随机对照试验的系统评价
BMC Infect Dis. 2016 Dec 12;16(1):749. doi: 10.1186/s12879-016-2063-4.
4
Systematic review and meta-analysis of randomized controlled trials of antibiotics and antiseptics for preventing infection in people receiving primary total hip and knee prostheses.抗生素和防腐剂预防初次全髋关节和膝关节置换患者感染的随机对照试验的系统评价和荟萃分析
Antimicrob Agents Chemother. 2015 Nov;59(11):6696-707. doi: 10.1128/AAC.01331-15. Epub 2015 Aug 10.
5
Preoperative skin antiseptics for preventing surgical wound infections after clean surgery.清洁手术术后预防手术伤口感染的术前皮肤消毒剂。
Cochrane Database Syst Rev. 2015 Apr 21;2015(4):CD003949. doi: 10.1002/14651858.CD003949.pub4.
6
Povidone-iodine: use in hand disinfection, skin preparation and antiseptic irrigation.聚维酮碘:用于手部消毒、皮肤准备及防腐冲洗。
Int Wound J. 2008 Jun;5(3):376-87. doi: 10.1111/j.1742-481X.2007.00405.x.
7
To dry or not to dry? An assessment of the possible degradation in efficiency of preoperative skin preparation caused by wiping skin dry.擦干还是不擦干?对擦干皮肤导致术前皮肤准备效率可能降低的评估。
Ann R Coll Surg Engl. 1993 May;75(3):181-5.
8
Skin preparation in the surgical patient.手术患者的皮肤准备
J Natl Med Assoc. 1988 Aug;80(8):899-904.