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基于纳米粒子的生物传感器在即时诊断中的应用进展。

Advancement in Nanoparticle-based Biosensors for Point-of-care In vitro Diagnostics.

机构信息

Univ Lyon, Université Claude Bernard Lyon-1, CNRS, ISA-UMR 5280, F-69622 Lyon, France.

Department of Basic Sciences, Deanship of Preparatory Year and Supporting Studies, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 34212, Saudi Arabia.

出版信息

Curr Top Med Chem. 2022;22(10):807-833. doi: 10.2174/1568026622666220401160121.

DOI:10.2174/1568026622666220401160121
PMID:35366774
Abstract

Recently, there has been great progress in the field of extremely sensitive and precise detection of bioanalytes. The importance of the utilization of nanoparticles in biosensors has been recognized due to their unique properties. Specifically, nanoparticles of gold, silver, and magnetic plus graphene, quantum dots, and nanotubes of carbon are being keenly considered for utilization within biosensors to detect nucleic acids, glucose, or pathogens (bacteria as well as a virus). Taking advantage of nanoparticles, faster and sensitive biosensors can be developed. Here, we review the nanoparticles' contribution to the biosensors field and their potential applications.

摘要

最近,在极其敏感和精确的生物分析物检测领域取得了重大进展。由于纳米粒子具有独特的性质,因此人们已经认识到在生物传感器中利用纳米粒子的重要性。具体而言,金、银和磁性加石墨烯纳米粒子、量子点以及碳纳米管正在被密切考虑用于生物传感器中以检测核酸、葡萄糖或病原体(细菌和病毒)。利用纳米粒子,可以开发出更快、更灵敏的生物传感器。在这里,我们回顾了纳米粒子对生物传感器领域的贡献及其潜在应用。

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