Department of Science Education, A. K. Education Faculty, Necmettin Erbakan University, Konya, Turkey.
Biomaterials and Biotechnology Laboratory, Science and Technology Research and Application Center (BITAM), Necmettin Erbakan University, Konya, Turkey.
Crit Rev Anal Chem. 2024;54(2):219-246. doi: 10.1080/10408347.2022.2072168. Epub 2022 May 9.
Bacterial and viruses pathogens are a significant hazard to human safety and health. In the imaging and detection of pathogenic microorganisms, the application of fluorescent nanoparticles is very useful. Carbon dots and quantum dots are preferred in this regard as labels, amplifiers, and/or electrode modifiers because of their outstanding features. However, precise diagnostics to identify numerous harmful bacteria simultaneously still face considerable hurdles, yet it is an inevitable issue. With the growing development of biosensors, nanoproduct-based bio-sensing has recently become one of the most promising methods for accurately identifying and quantifying various pathogens at low cost, high sensitivity, and selectivity, with time savings. The most recent applications of carbon dots in optical and electrochemical-based sensors are discussed in this review, along with some examples of pathogen sensors.HighlightsSimultaneous and early detection of pathogens is a critical issue in the management of readily spread to prevent epidemics.Carbon dots-based biosensors are more preferred in detection of pathogens due to high selectivity and sensitivity, as well as quick and cheap point-of-care platform.Summary of recent advances in the design of optical and electrochemical biosensors for the detection of pathogens.
细菌和病毒病原体对人类安全和健康构成重大威胁。在病原微生物的成像和检测中，荧光纳米粒子的应用非常有用。由于其突出的特点，碳点和量子点被优先用作标记物、放大器和/或电极修饰剂。然而，要精确诊断同时识别多种有害细菌仍然面临着相当大的障碍，但这是一个必然的问题。随着生物传感器的发展，基于纳米产品的生物传感最近已成为一种最有前途的方法，可以节省时间，以低成本、高灵敏度和选择性准确识别和定量各种病原体。本文综述了碳点在光学和电化学传感器中的最新应用，以及一些病原体传感器的例子。重点介绍了病原体的快速和早期同时检测是控制易传播疾病以预防流行病的关键问题。由于高选择性和灵敏度，以及快速、廉价的即时检测平台，基于碳点的生物传感器在病原体检测中更受欢迎。用于检测病原体的光学和电化学生物传感器设计的最新进展综述。
