Kim Sang-Yeob, Moon Byeong-Yeon, Cho Hyun Gug, Yu Dong-Sik
Department of Optometry, Kangwon National University, Samcheok, South Korea.
Front Neurosci. 2022 Mar 10;16:721665. doi: 10.3389/fnins.2022.721665. eCollection 2022.
Fixation stability for binocular anomalies with a phoria cannot be detected by direct observations. This study aimed to quantitatively evaluate fixation stability using an eye tracker rather than direct directions in binocular vision with abnormal and normal phorias.
Thirty-five and 25 participants with abnormal and normal phoria, respectively, were included in the study. The horizontal and vertical gaze points and convergence were recorded for 10 s using a remote eye tracker while binocularly viewing a target on a display screen 550 mm away. Fixation stability was quantified using bivariate contour ellipse areas (BCEA).
The fixation stability for all participants-based evaluations as a single cluster in the abnormal phoria group was lower than that in the normal phoria group ( = 0.005). There was no difference between the two groups in the evaluation based on the BCEA for each participant-based evaluation ( = 0.66). Fixation stability was also more related to convergence for the abnormal phoria group than for the normal phoria group ( = 0.769, < 0.001; = 0.417, = 0.038, respectively).
As the first study to evaluate fixation stability using an eye-tracker to differentiate between abnormal and normal phoria for non-strabismus, these findings may provide evidence for improving the evaluation of binocular vision not detected with clinical diagnostic tests.
对于伴有隐斜的双眼异常，无法通过直接观察检测到注视稳定性。本研究旨在使用眼动仪定量评估注视稳定性，而非在双眼视觉中通过直接观察来区分异常隐斜和正常隐斜。
本研究纳入了分别患有异常隐斜和正常隐斜的35名和25名参与者。使用远程眼动仪记录他们在双眼注视550毫米外显示屏上的目标时，水平和垂直注视点以及集合情况，持续10秒。使用双变量轮廓椭圆面积（BCEA）对注视稳定性进行量化。
在异常隐斜组中，将所有参与者作为一个整体进行评估时，注视稳定性低于正常隐斜组（P = 0.005）。在基于每个参与者的BCEA评估中，两组之间没有差异（P = 0.66）。与正常隐斜组相比，异常隐斜组的注视稳定性与集合的相关性也更高（分别为P = 0.769，P < 0.001；P = 0.417，P = 0.038）。
作为第一项使用眼动仪评估注视稳定性以区分非斜视性异常隐斜和正常隐斜的研究，这些发现可能为改进临床诊断测试未检测到的双眼视觉评估提供证据。
