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大鼠对模拟母乳营养成分的吸收及免疫调节研究

Study on the Absorption and Immunity Regulation of Simulated Breast Milk Nutrients in Rats.

作者信息

Xie Qinggang, Zhang Jinlan, Liu Yang, Yang Yi, Wei Yanli, Jiang Shilong, Cui Dongying, Zhou Qile

机构信息

Heilongjiang Feihe Dairy Co., Ltd., Beijing, China.

Beijing Institute of Nutritional Resources, Beijing Academy of Science and Technology, Beijing, China.

出版信息

Front Nutr. 2022 Mar 15;9:769846. doi: 10.3389/fnut.2022.769846. eCollection 2022.

DOI:10.3389/fnut.2022.769846
PMID:35369067
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8965348/
Abstract

Since infant formula (IF) manufacturers aim to produce a product as close to breast milk as possible, fortified nutrients are usually added. Generally, an IF is produced by adjusting the types and proportions of vitamins and minerals. This study comparatively examined the content of the six nutrients in different compound forms and evaluated the effect of different nutrient pack groups on immunity and growth. The results indicated that the simulated-human milk nutrients [minerals zinc (Zn), iron (Fe), calcium (Ca), and vitamins A, E, and B] were more easily absorbed by the body while effectively regulating immunity. This study provides a scientific foundation for developing, manufacturing, and applying imitation-breast formula milk powder.

摘要

由于婴儿配方奶粉(IF)制造商旨在生产尽可能接近母乳的产品,通常会添加强化营养素。一般来说,婴儿配方奶粉是通过调整维生素和矿物质的种类及比例来生产的。本研究比较了不同复合形式的六种营养素的含量,并评估了不同营养素包组对免疫力和生长的影响。结果表明,模拟人乳营养素[矿物质锌(Zn)、铁(Fe)、钙(Ca)以及维生素A、E和B]更容易被人体吸收,同时能有效调节免疫力。本研究为仿母乳配方奶粉的开发、生产和应用提供了科学依据。

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本文引用的文献

1
The new European regulatory framework for infant and follow-on formulas: Comments from the Committee of Nutrition of the French Society of Pediatrics (CN-SFP).欧洲关于婴儿配方奶粉和后续配方奶粉的新监管框架:法国儿科学会营养委员会(CN - SFP)的意见
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Evaluation of A Concentrated Preterm Formula as a Liquid Human Milk Fortifier in Preterm Babies at Increased Risk of Feed Intolerance.
评估一种浓缩早产儿配方作为液体人乳强化剂在有喂养不耐受风险的早产儿中的应用。
Nutrients. 2018 Oct 4;10(10):1433. doi: 10.3390/nu10101433.
4
Use of Stable Isotopes to Evaluate Bioefficacy of Provitamin A Carotenoids, Vitamin A Status, and Bioavailability of Iron and Zinc.使用稳定同位素评估类胡萝卜素维生素原 A、维生素 A 状态、铁和锌的生物有效性。
Adv Nutr. 2018 Sep 1;9(5):625-636. doi: 10.1093/advances/nmy036.
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Food synergies for improving bioavailability of micronutrients from plant foods.促进植物性食物中微量营养素生物利用率的食物协同作用。
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What's in the Bottle? A Review of Infant Formulas.瓶子里装的是什么?婴儿配方奶粉综述。
Nutr Clin Pract. 2016 Dec;31(6):723-729. doi: 10.1177/0884533616669362. Epub 2016 Sep 25.
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Breastfed at Tiffany's.在蒂芙尼吃母乳。
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9
Official Methods for the Determination of Minerals and Trace Elements in Infant Formula and Milk Products: A Review.婴儿配方奶粉和奶制品中矿物质及微量元素测定的官方方法:综述
J AOAC Int. 2016 Jan-Feb;99(1):42-52. doi: 10.5740/jaoacint.15-0246. Epub 2016 Jan 27.
10
Zinc absorption by young adults from supplemental zinc citrate is comparable with that from zinc gluconate and higher than from zinc oxide.年轻人补充柠檬酸锌的锌吸收率与葡萄糖酸锌相当,高于氧化锌。
J Nutr. 2014 Feb;144(2):132-6. doi: 10.3945/jn.113.181487. Epub 2013 Nov 20.