Liao Wenjing, Liu Suyu, Chen Yunxi, Kong Yashuai, Wang Dongxu, Wang Yijun, Ling Tiejun, Xie Zhongwen, Khalilova Irada, Huang Jinbao
State Key Laboratory of Tea Plant Biology and Utilization, School of Tea and Food Science and Technology, Anhui Agricultural University, Hefei, China.
School of Grain Science and Technology, Jiangsu University of Science and Technology, Zhenjiang, China.
Front Nutr. 2022 Mar 15;9:849582. doi: 10.3389/fnut.2022.849582. eCollection 2022.
The chemical compositions of black teas differ greatly and may have different health benefits; however, systematic investigations into such benefits are lacking. Here, the chemical profiles of Keemun black tea (KBT) and Dianhong black tea (DBT), two common categories of tea in China, were analyzed, and their lipid-lowering effects in male C57BL/6 mice fed a high-fat diet (60% energy from fat) or the diet supplemented with 2% black tea powder for 15 weeks were investigated. The compounds most crucial in differentiating KBT and DBT were determined to be phenolic compounds, theanine, and D-psicose. DBT was more effective than KBT in preventing excess hepatic fat accumulation. Both black teas effectively and comparably altered the mRNA levels of hepatic lipid-metabolizing genes. DBT had more favorable effects in stimulating fecal fat excretion than did KBT. The differentiating compounds with the higher values of variable importance in the projection (VIP) might predominantly contribute to the different health benefits; however, the most essential compound or combination of compounds requires clarification.
红茶的化学成分差异很大，可能具有不同的健康益处；然而，目前缺乏对这些益处的系统性研究。在此，我们分析了中国两种常见红茶——祁门红茶（KBT）和滇红红茶（DBT）的化学特征，并研究了它们对喂食高脂饮食（脂肪提供60%能量）或添加2%红茶粉的饮食15周的雄性C57BL/6小鼠的降脂作用。确定区分KBT和DBT的最关键化合物为酚类化合物、茶氨酸和D-阿洛酮糖。DBT在预防肝脏脂肪过度积累方面比KBT更有效。两种红茶均有效且相当程度地改变了肝脏脂质代谢基因的mRNA水平。DBT在促进粪便脂肪排泄方面比KBT具有更有利的作用。在投影中具有较高变量重要性值的区分化合物可能主要促成了不同的健康益处；然而，最关键的化合物或化合物组合仍需明确。
