埃塞俄比亚东北部莱加姆博地区育龄妇女停用依托孕烯皮下植入剂的早期决定因素：一项非匹配病例对照研究。

Determinants of early discontinuation of etonogestrel sub-dermal implant among reproductive-age women in Legambo district, Northeast Ethiopia: An unmatched case-control study.

作者信息

Yimer Yesuf, Cherie Niguss, Damtie Yitaysh

机构信息

Department of Reproductive and Family Health, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

出版信息

SAGE Open Med. 2022 Mar 29;10:20503121221088102. doi: 10.1177/20503121221088102. eCollection 2022.

DOI:10.1177/20503121221088102

PMID:35371479

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8969501/

Abstract

OBJECTIVE

Etonogestrel sub-dermal implant discontinuation is very common in the study area. But evidence on the determinants was limited. So, this study aimed to identify determinants of early discontinuation of etonogestrel sub-dermal implant among reproductive-age women in Legambo district, Northeast Ethiopia.

METHODS

An institution-based unmatched case-control study was conducted on 252 reproductive-age women (84 cases and 168 controls) from 1 February up to 30 April 2020. Systematic random sampling was used to select women, and the data were collected by face-to-face interview using a structured, pretested, and interviewer-administered questionnaire. The collected data were entered into Epi Data version 3.1 and analyzed by SPSS version 23. A binary logistic regression model was used to identify determinants of early discontinuation of etonogestrel sub-dermal implant. Statistical significance was declared at a value of less than 0.05, and adjusted odds ratio with a 95% confidence interval was used to identify determinants of early discontinuation of etonogestrel sub-dermal implant in the final model.

RESULT

In this study, not receiving pre-insertion counseling (adjusted odds ratio = 3.19, 95% confidence interval: (1.61, 6.30)), having a history of abortion (adjusted odds ratio = 2.89, 95% confidence interval: (1.50, 5.54)), contraceptive side effects (adjusted odds ratio = 2.45, 95% confidence interval: (1.99, 3.91)), and not receiving an appointment for a follow-up visit at the time of insertion (adjusted odds ratio = 3.45, 95% confidence interval: (1.89, 5.99)) were determinants of early discontinuation of etonogestrel sub-dermal implant.

CONCLUSION

Not receiving pre-insertion counseling, having a history of abortion, contraceptive side effects, and not receiving an appointment for a follow-up visit at the time of insertion were predictors of early discontinuation of etonogestrel sub-dermal implant. Thus, healthcare professionals should give an appointment for a follow-up visit at the time of insertion and provide detailed counseling for all women, not only for those who had had an abortion and contraceptive side effects.

摘要

目的

在研究地区，依托孕烯皮下植入剂停用的情况非常普遍。但关于其决定因素的证据有限。因此，本研究旨在确定埃塞俄比亚东北部莱加姆博区育龄妇女中依托孕烯皮下植入剂早期停用的决定因素。

方法

2020年2月1日至4月30日，在252名育龄妇女（84例病例和168例对照）中开展了一项基于机构的非匹配病例对照研究。采用系统随机抽样方法选取妇女，通过面对面访谈，使用一份结构化、经过预测试且由访谈员管理的问卷收集数据。收集到的数据录入Epi Data 3.1版本，并使用SPSS 23版本进行分析。采用二元逻辑回归模型确定依托孕烯皮下植入剂早期停用的决定因素。当P值小于0.05时声明具有统计学意义，并在最终模型中使用具有95%置信区间的调整后比值比来确定依托孕烯皮下植入剂早期停用的决定因素。

结果

在本研究中，未接受植入前咨询（调整后比值比=3.19，95%置信区间：(1.61, 6.30)）、有流产史（调整后比值比=2.89，95%置信区间：(1.50, 5.54)）、避孕药具副作用（调整后比值比=2.45，95%置信区间：(1.99, 3.91)）以及植入时未预约随访（调整后比值比=3.45，95%置信区间：(1.89, 5.99)）是依托孕烯皮下植入剂早期停用的决定因素。