[诺米芬辛：临床数据（作者译）]
[Nomifensine: clinical data (author's transl)].
作者信息
Clerc G, Cayreyre M
出版信息
Nouv Presse Med. 1978 Jun 28;7(26):2295-304.
Open studies with nomifensine the placebo, and double-blind controlled comparisons of nomifensine with placebo, imipramine, amitriptyline, nortriptyline... have been carried out in various parts of the world. Daily dosage varied (50-225 mg), lenght of treatment also (226 weeks). These trials showed considerable effectiveness of nomifensine in neurotic and reactive depressions, it counteracts inhibition and restores drive. Nomifensine caused no significant cardiovascular or anticholinergic side-effects. It does not potentiate the effect of alcohol.
已在世界各地开展了诺米芬辛与安慰剂的开放性研究，以及诺米芬辛与安慰剂、丙咪嗪、阿米替林、去甲替林的双盲对照比较研究。每日剂量各不相同（50 - 225毫克），治疗时长也不同（2 - 6周）。这些试验表明，诺米芬辛对神经症性抑郁和反应性抑郁有显著疗效，它能对抗抑制并恢复动力。诺米芬辛未引起明显的心血管或抗胆碱能副作用。它不会增强酒精的作用。
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