Division of Nephrology, New York University Langone Health and NYU Grossman School of Medicine, New York, New York.
Department of Medicine, New York City Health and Hospitals/Bellevue, New York, New York.
Kidney360. 2020 Oct 16;1(12):1345-1352. doi: 10.34067/KID.0005192020. eCollection 2020 Dec 31.
The COVID-19 pandemic strained hospital resources in New York City, including those for providing dialysis. New York University Medical Center and affiliations, including New York City Health and Hospitals/Bellevue, developed a plan to offset the increased needs for KRT. We established acute peritoneal dialysis (PD) capability, as usual dialysis modalities were overwhelmed by COVID-19 AKI.
Observational study of patients requiring KRT admitted to Bellevue Hospital during the COVID surge. Bellevue Hospital is one of the largest public hospitals in the United States, providing medical care to an underserved population. There were substantial staff, supplies, and equipment shortages. Adult patients admitted with AKI who required KRT were considered for PD. We rapidly established an acute PD program. A surgery team placed catheters at the bedside in the intensive care unit; a nephrology team delivered treatment. We provided an alternative to hemodialysis and continuous venovenous hemofiltration for treating patients in the intensive-care unit, demonstrating efficacy with outcomes comparable to standard care.
From April 8, 2020 to May 8, 2020, 39 catheters were placed into ten women and 29 men. By June 10, 39% of the patients started on PD recovered kidney function (average ages 56 years for men and 59.5 years for women); men and women who expired were an average 71.8 and 66.2 years old. No episodes of peritonitis were observed; there were nine incidents of minor leaking. Some patients were treated while ventilated in the prone position.
Demand compelled us to utilize acute PD during the COVID-19 pandemic. Our experience is one of the largest recently reported in the United States of which we are aware. Acute PD provided lifesaving care to acutely ill patients when expanding current resources was impossible. Our experience may help other programs to avoid rationing dialysis treatments in health crises.
COVID-19 大流行使纽约市的医院资源紧张,包括提供透析的资源。纽约大学医学中心及其附属机构,包括纽约市卫生与医院/贝尔维尤,制定了一项计划,以满足 KRT 需求的增加。我们建立了急性腹膜透析(PD)能力,因为常规透析方式已被 COVID-19 AKI 淹没。
对 COVID 高峰期间贝尔维尤医院收治的需要 KRT 的患者进行观察性研究。贝尔维尤医院是美国最大的公立医院之一,为服务不足的人群提供医疗服务。存在大量的人员、用品和设备短缺。因 AKI 需要 KRT 而入院的成年患者被考虑接受 PD。我们迅速建立了急性 PD 项目。一个手术团队在重症监护病房床边放置导管;一个肾病团队提供治疗。我们为重症监护病房的患者提供了替代血液透析和连续静脉-静脉血液滤过的方法,结果表明与标准治疗相当的疗效。
从 2020 年 4 月 8 日至 2020 年 5 月 8 日,10 名女性和 29 名男性共放置了 39 根导管。到 2020 年 6 月 10 日,39%开始接受 PD 的患者恢复了肾功能(男性平均年龄为 56 岁,女性为 59.5 岁);死亡的男性和女性平均年龄分别为 71.8 岁和 66.2 岁。未观察到腹膜炎发作;有 9 例轻微渗漏。有些患者在俯卧位通气时接受了治疗。
需求迫使我们在 COVID-19 大流行期间使用急性 PD。我们的经验是美国最近报告的最大经验之一,据我们所知。急性 PD 在无法扩大现有资源的情况下为急性重症患者提供了救生护理。我们的经验可能有助于其他计划在卫生危机期间避免透析治疗的配给。