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成人注意缺陷多动障碍:门诊精神科诊所患病率研究的系统评价和荟萃分析。

ADHD in Adults: A Systematic Review and Meta-Analysis of Prevalence Studies in Outpatient Psychiatric Clinics.

机构信息

Sligo Mental Health Services, Ireland.

University College Dublin, Ireland.

出版信息

J Atten Disord. 2022 Oct;26(12):1523-1534. doi: 10.1177/10870547221085503. Epub 2022 Apr 3.

Abstract

OBJECTIVE

Systematic review and meta-analysis to estimate the pooled prevalence of ADHD in adult attendees of outpatient mental health clinics and to investigate factors influencing prevalence rates.

METHODS

The following were extracted: demographics, design of the study (screening only or two-phase), scales/criteria for diagnosis of ADHD, number of ADHD, and non-ADHD participants.

RESULTS

The pooled prevalence of ADHD from screening studies ( = 9) was 26.7%, (95% CI [17.2-37.4]), ADHD = 1727, No ADHD = 3,578. From studies employing a two-stage design ( = 5), prevalence was 14.61%, CI [10.39-19.41], ADHD = 561, No ADHD = 3,578. Age and gender did not have any significant effect on the estimated prevalence. By contrast exclusion of psychotic disorders lowers prevalence. The screening scale used also influence prevalence rates.

CONCLUSION

Meta-analysis shows high rates of adult ADHD among psychiatric outpatient clinics. Applying DSM-5 criteria increased prevalence rates. More methodologically robust studies, using two-stage design, need to be conducted to help assist in service planning.

摘要

目的

系统评价和荟萃分析估计门诊精神卫生诊所成年就诊者中注意力缺陷多动障碍(ADHD)的患病率,并探讨影响患病率的因素。

方法

提取以下信息:人口统计学资料、研究设计(仅筛查或两阶段)、ADHD 的诊断量表/标准、ADHD 和非 ADHD 参与者的数量。

结果

来自筛查研究的 ADHD 总患病率为 26.7%(95%CI[17.2-37.4]),ADHD 患者=1727 人,非 ADHD 患者=3578 人。采用两阶段设计的研究(n=5)的患病率为 14.61%(95%CI[10.39-19.41]),ADHD 患者=561 人,非 ADHD 患者=3578 人。年龄和性别对估计的患病率没有任何显著影响。相比之下,排除精神障碍可降低患病率。所使用的筛查量表也会影响患病率。

结论

荟萃分析显示,在精神科门诊中,成年 ADHD 的发生率较高。应用 DSM-5 标准会增加患病率。需要进行更多采用两阶段设计、方法学更严谨的研究,以帮助制定服务计划。

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