Key Laboratory of Fermentation Engineering (Ministry of Education), National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan 430068, PR China.
College of Natural Resources and Environment, Northwest A&F University, Yangling, Shaanxi 712100, PR China.
Bioresour Technol. 2022 May;352:127105. doi: 10.1016/j.biortech.2022.127105. Epub 2022 Apr 2.
Lignocellulose waste was served as promising raw material for bioethanol production. Bioethanol was considered to be a potential alternative energy to take the place of fossil fuels. Lignocellulosic biomass synthesized by plants is regenerative, sufficient and cheap source for bioethanol production. The biotransformation of lignocellulose could exhibit dual significance-reduction of pollution and obtaining of energy. Some strategies are being developing and increasing the utilization of lignocellulose waste to produce ethanol. New technology of bioethanol production from natural lignocellulosic biomass is required. In this paper, the progress in genetic manipulation strategies including gene editing and synthetic genomics for the transformation from lignocellulose to ethanol was reviewed. At last, the application prospect of bioethanol was introduced.
木质纤维素废物可用作生产生物乙醇的有前景的原料。生物乙醇被认为是一种潜在的替代能源，可以替代化石燃料。植物合成的木质纤维素生物质是生产生物乙醇的可再生、充足且廉价的资源。木质纤维素的生物转化具有减少污染和获取能源的双重意义。一些策略正在被开发出来，以提高木质纤维素废物的利用率，生产乙醇。需要开发利用天然木质纤维素生物质生产生物乙醇的新技术。本文综述了从木质纤维素到乙醇转化的遗传操作策略的进展，包括基因编辑和合成基因组学。最后介绍了生物乙醇的应用前景。
