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超声心动图中二尖瓣腱索长度的建模作为其在手术室手动测量的函数。

Modeling of mitral chordae's length in echocardiography as a function of their manual measurement in the operating room.

机构信息

Department of Cardiology, Amiens Picardie University Hospital Center, 1 Rue du Professeur Christian CABROL, 80054, Amiens Cedex 1, France.

Department of Cardiac Surgery, Amiens Picardie University Hospital Center, 1 Rue du Professeur Christian CABROL, 80054, Amiens Cedex 1, France.

出版信息

J Cardiothorac Surg. 2022 Apr 4;17(1):64. doi: 10.1186/s13019-022-01816-8.

Abstract

OBJECTIVE

In mitral insufficiency, trans-esophageal echocardiography (TEE) analysis of the mitral valve is an indispensable and irreplaceable examination to establish precisely the type of surgical repair to be performed and the exact length of neo-chordae to be used for an anatomical repair. The aim of our study is to find a predictive model of the Echographic Measurement (EM) variable according to the Manual Measurement (MM) variable of the mitral valve chordae, when the echocardiography measurement is not feasible.

PATIENTS AND METHODS

This is a retrospective study on 191 patients undergoing mitral valve repair. The sex ratio (M/F) is 2.13 (130 men and 61 women). The collection of data of mitral chordae measurements performed echographically in preoperatively conditions, and then manually in intraoperatively conditions from January 2008 to December 2016 was made from the medical records of patients at the cardiology and cardiac surgery department of the University Hospital Center of Amiens in Picardy.

RESULTS

For this study 191 patients of mean age of 68 ± 13 years were included. The averages of the MM and EM of the mitral chordae were respectively 23 ± 2.5 mm and 24 ± 2.4 mm. The Pearson correlation coefficient was 0.897 (p-value < 10) showing a strong positive correlation between MM and EM. The results of the linear regression allow us to found the following mathematical model: EM = 0.87 × MM + 4.

CONCLUSIONS

When patients have a contraindication to transesophageal echocardiography or when TEE is not feasible, manual measurement is performed during the surgery. By using the values obtained (MM) in the model, it is possible to predict the corresponding echographic measurements. This allows us to achieve the mitral tendinous chordae substitution with a very high precision.

TRIAL REGISTRATION

Retrospectively registered.

摘要

目的

在二尖瓣关闭不全中,经食管超声心动图(TEE)分析二尖瓣是建立精确手术修复类型和用于解剖修复的确切新腱索长度所必需且不可替代的检查。我们研究的目的是找到一种根据二尖瓣腱索的手动测量(MM)变量预测超声测量(EM)变量的模型,当超声心动图测量不可行时。

患者和方法

这是一项回顾性研究,共纳入 191 例接受二尖瓣修复术的患者。男女比例为 2.13(130 名男性和 61 名女性)。从 2008 年 1 月至 2016 年 12 月,从皮卡第亚眠大学医院中心心内科和心脏外科患者的病历中收集了术前条件下经超声心动图测量和术中条件下手动测量的二尖瓣腱索数据。

结果

本研究共纳入 191 例平均年龄为 68±13 岁的患者。MM 和 EM 的平均二尖瓣腱索分别为 23±2.5mm 和 24±2.4mm。Pearson 相关系数为 0.897(p 值<10),表明 MM 和 EM 之间存在很强的正相关。线性回归的结果允许我们建立以下数学模型:EM=0.87×MM+4。

结论

当患者存在经食管超声心动图禁忌证或 TEE 不可行时,在手术期间进行手动测量。通过使用模型中获得的值(MM),可以预测相应的超声测量值。这使得我们能够非常精确地实现二尖瓣腱索替代。

试验注册

回顾性注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4108/8981775/2c33497fffc9/13019_2022_1816_Fig1_HTML.jpg

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