Physics Department, Mansoura University, Mansoura, Egypt.
Deanship of Scientific Research, Umm Al-Qura University, Makkah, Saudi Arabia.
Microsc Res Tech. 2022 Jul;85(7):2659-2668. doi: 10.1002/jemt.24120. Epub 2022 Apr 6.
Nowadays, due to the methodological needs in the application of internal surgery new methods evolving novel design for surgical suture are recommended. In this work, the effect of cold drawing process and the thermal annealing process on the different optical and structural properties of surgical suture fibers were studied. For the thermal annealing process, samples of Monosyn monofilaments suture fibers were thermally annealed at temperatures ranging from 50 to 100 for annealing time = 120 min. The thermal treatment was carried out under free end condition. For the cold drawing process, an Instron was used to mechanically draw and measures the tensile stress strain curve of Monosyn samples. Using differential scanning calorimetry, X-ray diffraction techniques, and optical polarizing microscope the different properties of the tested sutures, such as the crystallinity, sample radius, birefringence, molecular orientation, and tensile properties were measured. From the resulting data, there was a marked increase in the physical and structural properties during the thermal annealing and cold drawing processes. This means that a new reorientation of Monosyn suture molecular chains were performed and approved by calculating the different orientations f(θ) and f . This is an important improvement for these biodegradable materials to widen their medical use and improve their clinical results. RESEARCH HIGHLIGHTS: The stress-strain curve for Monosyn surgical fiber is J shape and identical to the human tissue stress-stain curve. The different orientation calculated improve that the drawing process affect directly on the fiber chain orientations. The fiber chains orientation due to the cold drawing process causes strain induced crystallinity.
如今，由于内科学应用中的方法学需要，建议采用新的方法设计新型外科缝线。在这项工作中，研究了冷拉伸工艺和热退火工艺对手术缝线纤维不同光学和结构性能的影响。对于热退火工艺，将 Monosyn 单丝缝线纤维的样品在 50 至 100 的温度范围内进行热退火，退火时间为 120 分钟。热处理在自由端条件下进行。对于冷拉伸工艺，使用 Instron 机械拉伸并测量 Monosyn 样品的拉伸应力-应变曲线。使用差示扫描量热法、X 射线衍射技术和光学偏光显微镜测量了测试缝线的不同性能，如结晶度、样品半径、双折射、分子取向和拉伸性能。从得到的数据中，可以看出在热退火和冷拉伸过程中物理和结构性能有明显提高。这意味着 Monosyn 缝线分子链发生了新的重排，并通过计算不同取向 f(θ)和 f 得到了证实。这是对这些可生物降解材料的重要改进，以扩大其医疗用途并提高其临床效果。研究亮点：Monosyn 外科纤维的应力-应变曲线呈 J 形，与人体组织的应力-应变曲线相同。计算出的不同取向表明，拉伸工艺直接影响纤维链的取向。由于冷拉伸工艺，纤维链的取向导致应变诱导结晶度。
