Department of Medical Imaging, Medical College of Yangtze University, Jingzhou, Hubei, China.
Department of Ultrasonography, Changsha Hospital for Maternal and Child Health Care, Changsha, Hunan, China.
J Obstet Gynaecol Res. 2022 Jul;48(7):1683-1690. doi: 10.1111/jog.15258. Epub 2022 Apr 5.
This study aimed to ascertain whether the lower anterior myometrial thickness (MT) between the bladder and the gestational sac in early pregnancy can be used to predict clinical outcomes in women with cesarean scar pregnancy (CSP) after expectant management.
We retrospectively analyzed the clinical data and early pregnancy ultrasound images of 21 patients who received expectant management for CSP. Among them, 11 patients with serious complications during pregnancy, such as intraoperative blood loss ≥1000 mL or with severe forms of morbidly adherent placenta (MAP; placenta increta or placenta percreta), were assigned to group A. The remaining 10 patients without serious complications during pregnancy were assigned to group B. The difference in MT between groups A and B was analyzed using nonparametric Mann-Whitney U test.
There was a statistically significant difference in MT between the groups (U = 20.000, p = 0.013). The area under the receiver operating characteristics (ROC) curve was 0.818, and the optimal cut-off value for MT was 3.3 mm.
Lower anterior MT around the gestational sac was correlated with severe complications, such as massive intraoperative bleeding or severe forms of MAP in patients with CSP.
本研究旨在确定妊娠早期膀胱与孕囊之间的前下子宫肌层厚度(MT)是否可用于预测期待管理后剖宫产瘢痕妊娠(CSP)患者的临床结局。
我们回顾性分析了 21 例接受期待管理的 CSP 患者的临床资料和早孕超声图像。其中,11 例患者在妊娠期间出现严重并发症,如术中出血量≥1000ml 或严重的黏附性胎盘(MAP;胎盘植入或胎盘穿透),归入 A 组。其余 10 例患者在妊娠期间无严重并发症,归入 B 组。采用非参数 Mann-Whitney U 检验分析 A、B 两组间 MT 的差异。
两组间 MT 存在统计学差异(U=20.000,p=0.013)。受试者工作特征(ROC)曲线下面积为 0.818,MT 的最佳截断值为 3.3mm。
妊娠早期孕囊周围前下 MT 与 CSP 患者大量术中出血或严重 MAP 等严重并发症相关。