Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Einstein (Sao Paulo). 2022 Apr 1;20:eRW5686. doi: 10.31744/einstein_journal/2022RW5686. eCollection 2022.
To develop a scientific consensus on nutrition in cystic fibrosis.
Sixteen coordinators elaborated relevant questions on nutritional therapy in cystic fibrosis, which were divided into six sections: nutritional assessment, nutritional recommendations, nutritional intervention, dietary counseling, special situations and enzyme replacement, and gastrointestinal manifestations. Two to three specialists in the field were responsible for each section and obtaining answers formulated based on standardized bibliographic searches. The available literature was searched in the PubMed®/MEDLINE database, after training and standardization of search strategies, to write the best level of evidence for the questions elaborated. Issues related to disagreement were discussed until a consensus was reached among specialists, based on the current scientific literature.
Forty-two questions were prepared and objectively answered, resulting in a consensus of nutritional therapy in cystic fibrosis.
This work enabled establishing a scientific consensus for nutritional treatment of cystic fibrosis patients.
就囊性纤维化的营养问题达成科学共识。
16 名协调员就囊性纤维化的营养治疗相关问题进行了阐述,分为六个部分:营养评估、营养建议、营养干预、饮食咨询、特殊情况和酶替代治疗以及胃肠道表现。每个部分由两到三位该领域的专家负责,并根据标准化文献检索制定答案。在培训和标准化搜索策略后,在 PubMed®/MEDLINE 数据库中搜索现有文献,为阐述的问题撰写最佳证据级别。对存在分歧的问题进行了讨论,最终根据当前的科学文献在专家之间达成共识。
共准备并客观回答了 42 个问题,从而达成了囊性纤维化营养治疗的共识。
这项工作为囊性纤维化患者的营养治疗奠定了科学基础。