Marhana Isnin Anang, Widianiti Kadek, Kusumastuti Etty Hary
Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Department of Anatomical Pathology, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Ann Med Surg (Lond). 2022 Mar 5;75:103423. doi: 10.1016/j.amsu.2022.103423. eCollection 2022 Mar.
The problem of establishing lung tumor diagnostics is a challenge for clinicians, especially pulmonologists, in determining a definitive diagnosis of a lung tumor.
Analyzing the conformity of anatomical pathology results between fine-needle aspiration biopsy (FNAB) and core needle biopsy (CNB) materials in peripheral lung tumors.
A cross-sectional study was conducted from July 2019 to December 2020 with 66 participants. Participants were examined for CNB and FNAB, in which the results of these examinations were compared for conformity. Statistical analysis used the Kappa test with < 0.05.
Most participants' tumor size was >70 mm, with FNAB results showing malignant category (39.5%), non-malignant (40.0%), and undiagnosed (38.9%; = 0.757). Meanwhile, CNB examination showed a tumor size of >70 mm that was categorized into malignant (40.4%) and non-malignant (33.3%; = 0.510). Most tumors were located in the right superior lobe that had FNAB results in the malignant (39.5%), non-malignant (30.0%) and undiagnosed (27.8%; = 0.306) categories. The CNB examination also showed that most tumors were located in the right superior lobe, which had resulted in the category of malignant (34.4%), non-malignant (26.7%), and undiagnosed (75.0%; = 0.240). Conformity of anatomical pathology results from FNAB and CNB subject such as malignancy category of 35 participants (74.5%), non-malignancy of 7 participants (53.8%) and undiagnosed of 4 participants (16.7%) with an accuracy of 69.69% ( = 0.43; = 0.001).
There is a conformity between the anatomical pathology results from FNAB and CNB materials for the diagnosis of lung tumors. CNB showed better results in the detection of anatomical malignancy and specimen adequacy.
对于临床医生，尤其是肺科医生而言，在确定肺肿瘤的明确诊断方面，建立肺肿瘤诊断方法是一项挑战。
分析外周肺肿瘤细针穿刺活检（FNAB）和粗针穿刺活检（CNB）材料的解剖病理学结果的一致性。
于2019年7月至2020年12月进行了一项横断面研究，共有66名参与者。对参与者进行了CNB和FNAB检查，并比较了这些检查结果的一致性。统计分析采用Kappa检验，P<0.05。
大多数参与者的肿瘤大小>70mm，FNAB结果显示恶性类别（39.5%）、非恶性（40.0%）和未确诊（38.9%；κ=0.757）。同时，CNB检查显示肿瘤大小>70mm的患者中，恶性分类为（40.4%），非恶性为（33.3%；κ=0.510）。大多数肿瘤位于右上叶，FNAB结果显示恶性（39.5%）、非恶性（30.0%）和未确诊（27.8%；κ=0.306）类别。CNB检查还显示，大多数肿瘤位于右上叶，其结果为恶性（34.4%）、非恶性（26.7%）和未确诊（75.0%；κ=0.240）。35名参与者（74.5%）的FNAB和CNB解剖病理学结果在恶性类别方面的一致性、7名参与者（53.8%）在非恶性方面的一致性以及4名参与者（16.7%）在未确诊方面的一致性，准确率为69.69%（κ=0.43；P=0.001）。
FNAB和CNB材料的解剖病理学结果在肺肿瘤诊断方面具有一致性。CNB在检测解剖学恶性肿瘤和标本充足性方面显示出更好的结果。
