Research Institute of Integrative Life Sciences, Dongguk University-Seoul, Goyang-si, Gyeonggi-do 10326, Republic of Korea.
Department of Life Science & Bioinformatics, Assam University, Silchar-11, India.
Comb Chem High Throughput Screen. 2023;26(2):256-288. doi: 10.2174/1386207325666220406110404.
The Apiaceae or Umbelliferae is one of the largest families in terms of species representation in the plant kingdom. It is also a prominent family in the field of phytochemicals and pharmacology. The family is also quite prominent in the production of spices and condiments and food supplements in nutrition, aside from the potential of species in the family to induce apoptotic, antimicrobial, antitumor, and hepatoprotective activities.
This work presents a detailed structural elucidation and functional aspects of phytochemicals from the Apiaceae or Umbelliferae family.
Furthermore, the application of members of this family in traditional and modern pharmacology is emphasized. This review also highlights the linkage of phytochemicals used in the conventional system of medication for the development of novel therapeutics through a chain of pre-clinical and clinical trials.
This study may represent a valuable step ahead in the clinical development of natural drugs for curing several ailments, including respiratory and virus-related diseases.
伞形科是植物界中物种多样性最丰富的科之一。在植物化学和药理学领域，它也是一个重要的家族。该科在香料、调味品和营养食品补充剂的生产方面也相当突出，此外，该科的某些物种还具有诱导细胞凋亡、抗菌、抗肿瘤和保肝活性的潜力。
本工作对伞形科植物化学物质的结构阐明和功能方面进行了详细介绍。
此外，还强调了该科成员在传统和现代药理学中的应用。本综述还强调了通过一系列临床前和临床试验，将传统药物体系中使用的植物化学物质用于开发新疗法的联系。
本研究可能是在临床开发天然药物治疗多种疾病（包括呼吸道和病毒相关疾病）方面向前迈出的有价值的一步。
