Biology Department, Faculty of Science, University of Porto, Rua Do Campo Alegre S/n, 4169-007, Porto, Portugal; GreenUPorto - Sustainable Agrifood Production, Research Centre, Department of Biology, Faculty of Science, University of Porto, Rua Do Campo Alegre S/n, 4169-007, Porto, Portugal; CITAB, Centre for the Research and Technology of Agro-Environmental and Biological Sciences, Universidade de Trás-os-Montes e Alto Douro, 5000-801, Vila Real, Portugal.
CITAB, Centre for the Research and Technology of Agro-Environmental and Biological Sciences, Universidade de Trás-os-Montes e Alto Douro, 5000-801, Vila Real, Portugal; Biology Department & CBMA - Centre of Molecular and Environmental Biology (CBMA), School of Sciences, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal; CEB - Centre of Biological Engineering, University of Minho, 4710-057, Braga, Portugal.
Phytochemistry. 2021 Jul;187:112714. doi: 10.1016/j.phytochem.2021.112714. Epub 2021 Apr 10.
The Apiaceae Lindl. (=Umbelliferae Juss.), which includes several economical important vegetables, herbs, and spices, is one of the most numerous plant family. Umbelliferous crops (namely anise, fennel, carrot, coriander, parsley, etc.) are also valuable sources of botanical flavoring agents and fragrances. In addition, Apiaceae species yield a wide variety of distinctive specialized metabolites (i.e, volatile phenylpropanoids, furanocoumarins, sesquiterpene coumarins, polyacetylenes, and phthalides), some of them been described as uncommon natural phytochemicals exclusive of the family, which offers a great potential for bioprospection. Numerous studies have pointed out the outstanding biological activity of extracts and several classes of phytochemicals from Apiaceae species. Emphasis has been given to essential oils (EOs) and their constituents activities, most likely because this type of plant added value product benefits from a larger acceptance and application potential in integrated pest management (IPM) and integrated vector management (IVM) programs. Several species of the family offer a variety of unique compounds with great potential as biopesticidal and/or synergizing agents. Investigations covering their activity toward agricultural pests and phytopathogens have increased in the last years, nevertheless the interest remains strongly focus on arthropod species, predominantly those acting as vectors of human diseases. From our survey, it is patent the gap of knowledge concerning the potential molluscicidal properties of Apiaceae extracts/phytochemicals, as well as their herbicidal activities against invasive plant species. In this review, we propose to highlight the potential of Apiaceae species as suitable sources of bioactive phytochemicals with great relevance within the frame of plant-based pesticides R&D, and will discuss their applicability in real-world scenarios considering the recent developments regarding the design of stable formulations incorporating Apiaceae bioactive products. We expect that this review will encourage researchers to consider undervalued Apiaceae species as alternative sources of bioactive compounds and will give a contribute to the field by suggesting new research topics.
伞形科（Lindl.）（=伞形科 Juss.），包括几种经济重要的蔬菜、草药和香料，是植物科中最多的一科之一。伞形科作物（即八角、茴香、胡萝卜、芫荽、欧芹等）也是植物调味剂和香料的有价值来源。此外，伞形科植物产生广泛的独特的特殊代谢物（即挥发性苯丙素、呋喃香豆素、倍半萜香豆素、多炔和苯酞），其中一些被描述为伞形科特有的不常见天然植物化学物质，这为生物勘探提供了巨大的潜力。许多研究指出了伞形科植物提取物和几类植物化学物质的突出生物活性。重点放在精油（EOs）及其成分的活性上，这很可能是因为这种植物附加值产品在综合害虫管理（IPM）和综合病媒管理（IVM）计划中具有更大的接受度和应用潜力。该科的几种物种提供了各种具有巨大作为生物农药和/或增效剂潜力的独特化合物。近年来，对其防治农业害虫和植物病原菌活性的研究有所增加，但兴趣仍然强烈集中在节肢动物物种上，主要是那些作为人类疾病媒介的物种。从我们的调查中可以看出，有关伞形科提取物/植物化学物质潜在杀软体动物特性以及它们对入侵植物物种的除草活性的知识仍然存在很大的差距。在这篇综述中，我们建议强调伞形科植物作为具有生物活性的植物化学物质的合适来源的潜力，这些植物化学物质在基于植物的农药研发框架内具有重要意义，并将讨论它们在实际情况下的适用性，考虑到最近关于包含伞形科生物活性产品的稳定制剂设计的发展。我们希望这篇综述将鼓励研究人员将被低估的伞形科植物视为生物活性化合物的替代来源，并通过提出新的研究课题为该领域做出贡献。
