Dell'Osso Liliana, Toschi Daniela, Amatori Giulia, Gesi Camilla
Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Department of Psychiatry and Addiction, ASST Fatebenefratelli-Sacco, Milan, Italy.
CNS Neurol Disord Drug Targets. 2023;22(4):462-465. doi: 10.2174/1871527321666220406105844.
Initially conceptualized as a subtype of schizophrenia, catatonia has progressively been recognized to occur in a wide variety of conditions as a kind of final common pathway for many severe mental disorders. There is a significant overlap between the fundamental symptoms of autism spectrum disorder (ASD) and catatonia, and ASD can frequently complicate catatonic states. While provocative, the hypothesis that neuroatypicality may represent the submerged structural piece underlying catatonic states is intriguing. Yet, the multifaced relationship between catatonia and ASD may provide new insights into the etiology and treatment of both disorders.
紧张症最初被概念化为精神分裂症的一种亚型,如今已逐渐被认识到它会在多种病症中出现,是许多严重精神障碍的一种终末共同途径。自闭症谱系障碍(ASD)的基本症状与紧张症之间存在显著重叠,且ASD常常会使紧张症状态复杂化。虽然具有启发性,但关于神经非典型性可能代表紧张症状态潜在结构基础的假说很有意思。然而,紧张症与ASD之间的多方面关系可能会为这两种疾病的病因和治疗提供新的见解。