J Drugs Dermatol. 2022 Apr 1;21(4):s3-s10.
The term "exposome" describes the totality of exposures an individual is subjected to from conception to death. Both internal and external exposome factors affect skin health. External exposures that contribute to facial skin aging include solar radiation, air pollution, tobacco smoke, and unbalanced nutrition. The review explores scientific and clinical insights into the exposome impact on facial skin aging and topical mineralizing volcanic water use potential benefits.
An expert panel of seven dermatologists and two clinical researchers specializing in aesthetic and dermatological indications reviewed and discussed the literature on the exposome and mineralizing volcanic water's role in relation to the exposome. Two virtual advisory boards were conducted between February and May 2021. Following the meetings, an additional systematic literature review explored publications relevant to the exposome, topical essential minerals, and skin health. The results of the two advisory boards, coupled with expert opinion and the outcome of the updated systematic literature review, informed the statements on which the advisors reached a consensus.
A combination of in vivo, in vitro, and clinical data on topical mineralizing volcanic water application indicates that the serum supports the skin's antioxidant defenses and reduces skin inflammation. Additionally, the serum may have benefits as an adjunct for facial dermatoses and post-procedural skincare. J Drugs Dermatol. 2022;21:4(Suppl 1):s3-10.
“暴露组”一词描述了个体从受孕到死亡所经历的所有暴露。内部和外部的暴露组因素都会影响皮肤健康。导致面部皮肤衰老的外部暴露因素包括太阳辐射、空气污染、烟草烟雾和营养失衡。本综述探讨了暴露组对面部皮肤衰老的影响以及矿物化火山水应用的潜在益处的科学和临床见解。
由 7 名皮肤科医生和 2 名专门研究美容和皮肤科适应症的临床研究人员组成的专家小组审查并讨论了关于暴露组和矿物化火山水在暴露组中的作用的文献。在 2021 年 2 月至 5 月期间进行了两次虚拟顾问会议。会议结束后,进行了额外的系统文献综述,以探讨与暴露组、局部必需矿物质和皮肤健康相关的出版物。两次顾问会议的结果,加上专家意见和更新的系统文献综述的结果,为顾问达成共识的陈述提供了信息。
关于局部矿物化火山水应用的体内、体外和临床数据的综合结果表明,该血清支持皮肤的抗氧化防御能力,并减少皮肤炎症。此外,该血清可能有益于面部皮肤病和术后皮肤护理。J 皮肤病药物学杂志。2022;21:4(增刊 1):s3-10。