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肤色人群皮肤衰老外显组学:文献综述。

Skin Aging Exposome in Skin of Color Populations: Review of the Literature.

机构信息

Tishreen University School of Medicine, Latakia, Syria.

Professor of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

出版信息

Dermatol Surg. 2023 Mar 1;49(3):272-277. doi: 10.1097/DSS.0000000000003704. Epub 2023 Feb 2.

Abstract

BACKGROUND

As life expectancy increases, the comorbidities related to aging require greater attention. Skin aging exposomes were only recently defined and need additional delineation, particularly in Skin of Color (SOC) populations.

OBJECTIVE

The primary objective is to shed the light and summarize the existing literature on skin aging exposome in SOC populations.

MATERIALS AND METHODS

We performed an extensive search in the PubMed and Google Scholar databases. We included peer-reviewed studies in SOC populations around the world regarding one or more of the skin aging exposome factors, and we grouped and organized the studies under each factor of the skin aging exposome.

RESULTS

Some environmental exposome factors are preventable or modifiable, for example, by applying broad-spectrum sunscreens with visible light protection, improving nutrition, and smoking cessation. Other factors such as air pollution will require more complex solutions. Our search revealed a paucity of references on skin aging exposome factors in SOC populations.

CONCLUSION

We identified the need for more dedicated studies in SOC populations to advance knowledge on skin aging exposome factors. This knowledge will provide a better understanding of approaches to minimize extrinsic skin aging in these populations.

摘要

背景

随着预期寿命的延长,与衰老相关的合并症需要更多的关注。皮肤衰老暴露组学最近才被定义,需要进一步描述,特别是在有色人种(SOC)人群中。

目的

主要目的是阐明和总结 SOC 人群皮肤衰老暴露组学的现有文献。

材料和方法

我们在 PubMed 和 Google Scholar 数据库中进行了广泛的检索。我们纳入了全球 SOC 人群中关于一个或多个皮肤衰老暴露组学因素的同行评议研究,并根据皮肤衰老暴露组学的每个因素对这些研究进行了分组和组织。

结果

一些环境暴露组学因素是可以预防或改变的,例如,使用具有可见光保护的广谱防晒霜、改善营养和戒烟。其他因素,如空气污染,将需要更复杂的解决方案。我们的搜索结果表明,SOC 人群中皮肤衰老暴露组学因素的参考文献相对较少。

结论

我们发现需要在 SOC 人群中进行更多专门的研究,以推进对皮肤衰老暴露组学因素的认识。这一知识将有助于更好地了解在这些人群中减少外在皮肤衰老的方法。

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