Yuan Fan, Xia Youyuan, Lu Qin, Xu Qin, Shu Yun, Hu Xiaoya
School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, 225002, PR China.
School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, 225002, PR China.
Talanta. 2022 Jul 1;244:123419. doi: 10.1016/j.talanta.2022.123419. Epub 2022 Mar 29.
The flexible electrochemical sensor is a key component of the health monitoring system which can continuously track the physiological signals of the human body, while there is no obvious discomfort and invasiveness. Therefore, it has great potential in personalized medical testing. However, the development of flexible electrochemical sensors currently faces many difficulties, such as the limitations of conductive material properties and manufacturing methods, and the disadvantages of commonly used flexible substrates that are not resistant to high temperatures. In this work, inorganic nanomaterials commonly used to make flexible electrochemical sensors were classified to zero-dimensional (0D) nanomaterials, one-dimensional (1D) nanomaterials, two-dimensional (2D) nanomaterials, and hybrid nanomaterials according to their morphology. The fabrication method of the nanomaterials-based flexible electrochemical sensors was also introduced. Furthermore, the application of flexible electrochemical sensors for chemical and biological sensing and their detection performance were summarized. The detection targets were classified to ion, small molecule, biomacromolecule, and bacteria, respectively.
柔性电化学传感器是健康监测系统的关键部件，它能够持续跟踪人体的生理信号，同时不会给人带来明显不适且无侵入性。因此，它在个性化医学检测方面具有巨大潜力。然而，目前柔性电化学传感器的发展面临诸多困难，例如导电材料性能和制造方法的局限性，以及常用柔性基底不耐高温的缺点。在这项工作中，常用于制造柔性电化学传感器的无机纳米材料根据其形态被分类为零维（0D）纳米材料、一维（1D）纳米材料、二维（2D）纳米材料和混合纳米材料。还介绍了基于纳米材料的柔性电化学传感器的制造方法。此外，总结了柔性电化学传感器在化学和生物传感方面的应用及其检测性能。检测目标分别被分类为离子、小分子、生物大分子和细菌。
