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[顺势疗法药物对人粒细胞吞噬活性的影响。对照单盲研究中的体外试验]

[Effect of homeopathic drugs on the phagocytic activity of human granulocytes. In vitro tests in a controlled single-blind study].

作者信息

Wagner H, Jurcic K, Doenicke A, Rosenhuber E, Behrens N

出版信息

Arzneimittelforschung. 1986 Sep;36(9):1421-5.

PMID:3539129
Abstract

Four homeopathic drug preparations with extract dilutions between D1 and D30 (expression for the homeopathic grade of potencies) and some additives (minerals and animal toxins) were investigated, using two in vitro and one in vivo phagocytosis models. All preparations enhanced significantly the activity of phagocytosis in all used systems. In controlled prospective single-blind studies with the preparations C and D performed on 12 and 14 verum and 13 male placebo volunteers respectively with i.v. injections within a 5-day treatment the phagocytosis indices were measured during 11 days using the microscopic smear method. In both investigations the maximum of phagocytosis activity was reached between the 4th and 5th day of injection. After the 4th or 5th (next to the last or last) injection, a rapid decrease of activity occurred which reached normal values on the 11th day. Other laboratory parameters investigated were not influenced.

摘要

对四种顺势疗法制剂进行了研究,其提取物稀释度在D1至D30之间(顺势疗法效力等级的表示方法),还含有一些添加剂(矿物质和动物毒素),采用了两种体外和一种体内吞噬作用模型。所有制剂在所有使用的系统中均显著增强了吞噬作用的活性。在分别对12名和14名接受真药治疗的志愿者以及13名男性安慰剂志愿者进行的制剂C和D的对照前瞻性单盲研究中,通过静脉注射,在为期5天的治疗期间,使用显微镜涂片法在11天内测量吞噬指数。在两项研究中,吞噬作用活性在注射后第4天和第5天达到最大值。在第4次或第5次(倒数第二次或最后一次)注射后,活性迅速下降,并在第11天恢复到正常值。所研究的其他实验室参数未受影响。

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Arzneimittelforschung. 1986 Sep;36(9):1421-5.
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Echinacea for preventing and treating the common cold.紫锥菊用于预防和治疗普通感冒。
Cochrane Database Syst Rev. 2014 Feb 20;2014(2):CD000530. doi: 10.1002/14651858.CD000530.pub3.
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Mechanical agitation of very dilute antiserum against IgE has no effect on basophil staining properties.用机械方法搅拌针对IgE的极稀抗血清,对嗜碱性粒细胞的染色特性没有影响。
Experientia. 1992 May 15;48(5):504-8. doi: 10.1007/BF01928175.