Usui Y, Ichiman Y, Yoshida K, Oikawa K
Br J Exp Pathol. 1986 Oct;67(5):629-35.
A hydrochloric acid extract, the clumping factor fraction, obtained from a clumping factor-positive strain of group B streptococci, was capable of killing mice by administration after injection of heat-killed cells of group B streptococci or Escherichia coli intravenously. In mice killed between 24 and 48 h later, fibrin thrombi were observed in the renal glomeruli, as well as in the heart, lung, liver, and pancreas. These findings suggest the possible induction of disseminated intravascular coagulation by these organisms in the mouse.
从B组链球菌的一个凝聚因子阳性菌株获得的盐酸提取物——凝聚因子部分，在静脉注射B组链球菌或大肠杆菌的热灭活细胞后给药，能够杀死小鼠。在24至48小时后处死的小鼠中，在肾小球以及心脏、肺、肝脏和胰腺中观察到纤维蛋白血栓。这些发现提示这些微生物在小鼠中可能诱导弥散性血管内凝血。
