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孟加拉国城市贫困人群中与高血压相关的因素在年龄和性别上的差异。

Age and sex differences in factors associated with hypertension among an urban poor population in Bangladesh.

机构信息

Department of Public Health and Health Systems, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Department of Public Health and Informatics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.

出版信息

Nagoya J Med Sci. 2022 Feb;84(1):69-79. doi: 10.18999/nagjms.84.1.69.

Abstract

This study explores the differences in factors associated with hypertension between younger and older subjects in an urban slum community in Bangladesh. We analyzed the data of 1,008 men and 1,001 women obtained from a cross-sectional survey conducted between October 2015 and April 2016. Multivariable logistic regression models were stratified by age (18 to 44 and 45 to 64 years) in men and women separately. The multivariable model included age (continuous) and the following categorical variables simultaneously: education duration, marital status, tobacco smoking, smokeless tobacco use, total physical activity, body mass index (BMI), waist circumference, and the blood levels of glycated hemoglobin (HbA1c), triglycerides, high- and low-density lipoprotein (HDL and LDL) cholesterol. Hypertension was defined as the presence of either blood pressure ≥140/90 mmHg or the use of antihypertensive medication. The prevalence of hypertension was 13.0% (younger men), 14.6% (younger women), 35.6% (older men), and 38.7% (older women). In younger men, higher waist circumference and increased LDL cholesterol levels were significantly associated with hypertension. In older men, physical activity was the only significant factor that was inversely associated with hypertension. In younger women, higher BMI, increased HbA1c, triglycerides, and LDL cholesterol levels were associated with hypertension. In older women, a higher HbA1c was the only factor significantly associated with hypertension. These findings suggest that public health interventions to prevent hypertension may require different approaches according to sex and age groups within the poor urban population in Bangladesh.

摘要

本研究探讨了孟加拉国一个城市贫民窟社区中年轻和老年人群体中与高血压相关的因素差异。我们分析了 2015 年 10 月至 2016 年 4 月期间进行的横断面调查中获得的 1008 名男性和 1001 名女性的数据。多变量逻辑回归模型按男性和女性的年龄(18 至 44 岁和 45 至 64 岁)分层。多变量模型包括年龄(连续)和以下分类变量同时:教育持续时间、婚姻状况、吸烟、无烟烟草使用、总体力活动、体重指数(BMI)、腰围以及糖化血红蛋白(HbA1c)、甘油三酯、高低密度脂蛋白(HDL 和 LDL)胆固醇的血液水平。高血压定义为血压≥140/90mmHg 或使用抗高血压药物。高血压的患病率为 13.0%(年轻男性)、14.6%(年轻女性)、35.6%(老年男性)和 38.7%(老年女性)。在年轻男性中,较高的腰围和较高的 LDL 胆固醇水平与高血压显著相关。在老年男性中,体力活动是唯一与高血压呈负相关的显著因素。在年轻女性中,较高的 BMI、较高的 HbA1c、甘油三酯和 LDL 胆固醇水平与高血压相关。在老年女性中,较高的 HbA1c 是唯一与高血压显著相关的因素。这些发现表明,在孟加拉国贫困城市人口中,根据性别和年龄组,预防高血压的公共卫生干预措施可能需要采取不同的方法。

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1
The global epidemiology of hypertension.高血压的全球流行病学。
Nat Rev Nephrol. 2020 Apr;16(4):223-237. doi: 10.1038/s41581-019-0244-2. Epub 2020 Feb 5.
2
Sex differences in cardiometabolic disorders.心脏代谢疾病的性别差异。
Nat Med. 2019 Nov;25(11):1657-1666. doi: 10.1038/s41591-019-0643-8. Epub 2019 Nov 7.

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