接种 BNT162b2 mRNA COVID-19 疫苗后免疫功能正常的成人水痘-带状疱疹病毒（VZV）脑膜炎：病例报告。
Varicella-Zoster Virus (VZV) Meningitis in an Immunocompetent Adult after BNT162b2 mRNA COVID-19 Vaccination: A Case Report.
机构信息
Associate Staff Physician, Hospital Medicine, Medical Subspecialties Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE, p.o box 112412.
AAHIVP, Senior Manager, Pharmacy Education and Training, Co-Director, Antimicrobial Stewardship Program, Department of Pharmacy Services, Cleveland Clinic Abu Dhabi, UAE. p.o box 112412.
出版信息
Int J Infect Dis. 2022 Jun;119:184-186. doi: 10.1016/j.ijid.2022.04.001. Epub 2022 Apr 6.
Abstract
We present, to our knowledge, the second case report of a 46-year old female who developed varicella-zoster virus (VZV) meningitis after BNT162b2 mRNA COVID-19 vaccination. The patient is immunocompetent and has no known predisposing risk factors for developing VZV meningitis. The patient received acyclovir therapy and subsequently had a complete recovery. We describe possible mechanisms of VZV meningitis after mRNA COVID-19 vaccination.
摘要
我们报告了第二例已知病例，一名 46 岁女性在接种 BNT162b2 mRNA COVID-19 疫苗后发生水痘带状疱疹病毒 (VZV) 脑膜炎。患者免疫功能正常，且无已知易患 VZV 脑膜炎的危险因素。患者接受了阿昔洛韦治疗，随后完全康复。我们描述了 mRNA COVID-19 疫苗接种后 VZV 脑膜炎的可能发病机制。
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