Tagorti Ghada, Kaya Bülent
Department of Biology, Faculty of Sciences, Akdeniz University, 07058 Campus, Antalya, Turkey.
Genomics Inform. 2022 Mar;20(1):e10. doi: 10.5808/gi.21083. Epub 2022 Mar 31.
Human exposure to pollutants has been on the rise. Thus, researchers have been focused on understanding the effect of these compounds on human health, especially on the genetic information by using various tests, among them the somatic mutation and recombination tests (SMARTs). It is a sensitive and accurate method applicable to genotoxicity analysis. Here, a comprehensive bibliometric analysis of SMART assays in genotoxicity studies was performed to assess publication trends of this field. Data were extracted from the Web of Science database and analyzed by the bibliometric tools HistCite, Biblioshiny (RStudio), VOSViewer, and CiteSpace. Results have shown an increase in the last 10 years in terms of publication. A total of 392 records were published in 96 sources mainly from Brazil, Spain, and Turkey. Research collaboration networks between countries and authors were performed. Based on document co-citation, five large research clusters were identified and analyzed. The youngest research frontier emphasized on nanoparticles. With this study, how research trends evolve over years was demonstrated. Thus, international collaboration could be enhanced, and a promising field could be developed.
人类接触污染物的情况一直在增加。因此,研究人员一直专注于通过各种测试来了解这些化合物对人类健康的影响,特别是对遗传信息的影响,其中包括体细胞突变和重组测试(SMARTs)。它是一种适用于遗传毒性分析的灵敏且准确的方法。在此,对遗传毒性研究中的SMART分析进行了全面的文献计量分析,以评估该领域的出版趋势。数据从科学网数据库中提取,并通过文献计量工具HistCite、Biblioshiny(RStudio)、VOSViewer和CiteSpace进行分析。结果显示,在过去10年中出版物数量有所增加。共有392条记录发表在96个来源上,主要来自巴西、西班牙和土耳其。开展了国家和作者之间的研究合作网络。基于文献共被引,识别并分析了五个大型研究集群。最年轻的研究前沿侧重于纳米颗粒。通过这项研究,展示了多年来研究趋势是如何演变的。因此,可以加强国际合作,并开拓一个有前景的领域。